# STOCKHOLM 1.0
#=GF ID 3.30.565.10/FF/000136
#=GF DE DNA topoisomerase 2
#=GF AC 3.30.565.10/FF/000136
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 26.889
#=GS Q383C4/13-255      AC Q383C4
#=GS Q383C4/13-255      OS Trypanosoma brucei brucei TREU927
#=GS Q383C4/13-255      DE DNA topoisomerase 2
#=GS Q383C4/13-255      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; 
#=GS Q383C4/13-255      DR GO; GO:0003918; GO:0005634; GO:0005654; GO:0006265; GO:0044877; 
#=GS Q4Q836/12-252      AC Q4Q836
#=GS Q4Q836/12-252      OS Leishmania major
#=GS Q4Q836/12-252      DE DNA topoisomerase 2
#=GS Q4Q836/12-252      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; 
#=GS Q4Q836/12-252      DR GO; GO:0005634; 
#=GS A0A0N0DZD8/12-253  AC A0A0N0DZD8
#=GS A0A0N0DZD8/12-253  OS Leptomonas pyrrhocoris
#=GS A0A0N0DZD8/12-253  DE DNA topoisomerase 2
#=GS A0A0N0DZD8/12-253  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leptomonas; Leptomonas pyrrhocoris; 
#=GS A0A0N1HUJ9/12-252  AC A0A0N1HUJ9
#=GS A0A0N1HUJ9/12-252  OS Leptomonas seymouri
#=GS A0A0N1HUJ9/12-252  DE DNA topoisomerase 2
#=GS A0A0N1HUJ9/12-252  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leptomonas; Leptomonas seymouri; 
#=GS A4HGT2/12-253      AC A4HGT2
#=GS A4HGT2/12-253      OS Leishmania braziliensis
#=GS A4HGT2/12-253      DE DNA topoisomerase 2
#=GS A4HGT2/12-253      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; 
#=GS D0A926/13-255      AC D0A926
#=GS D0A926/13-255      OS Trypanosoma brucei gambiense DAL972
#=GS D0A926/13-255      DE DNA topoisomerase 2
#=GS D0A926/13-255      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei gambiense; 
#=GS E9BJW5/12-253      AC E9BJW5
#=GS E9BJW5/12-253      OS Leishmania donovani BPK282A1
#=GS E9BJW5/12-253      DE DNA topoisomerase 2
#=GS E9BJW5/12-253      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; 
#=GS E9B049/12-253      AC E9B049
#=GS E9B049/12-253      OS Leishmania mexicana MHOM/GT/2001/U1103
#=GS E9B049/12-253      DE DNA topoisomerase 2
#=GS E9B049/12-253      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; 
#=GS A0A088RVC5/12-253  AC A0A088RVC5
#=GS A0A088RVC5/12-253  OS Leishmania panamensis
#=GS A0A088RVC5/12-253  DE DNA topoisomerase 2
#=GS A0A088RVC5/12-253  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania panamensis; 
#=GS A4I3V9/12-253      AC A4I3V9
#=GS A4I3V9/12-253      OS Leishmania infantum
#=GS A4I3V9/12-253      DE DNA topoisomerase 2
#=GS A4I3V9/12-253      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; 
#=GS A0A3Q8II93/12-253  AC A0A3Q8II93
#=GS A0A3Q8II93/12-253  OS Leishmania donovani
#=GS A0A3Q8II93/12-253  DE DNA topoisomerase 2
#=GS A0A3Q8II93/12-253  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; 
#=GS A0A3P3ZB29/12-253  AC A0A3P3ZB29
#=GS A0A3P3ZB29/12-253  OS Leishmania braziliensis MHOM/BR/75/M2904
#=GS A0A3P3ZB29/12-253  DE DNA topoisomerase 2
#=GS A0A3P3ZB29/12-253  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; 
#=GF SQ 12
Q383C4/13-255              KTQHEHILARPDMYIGTIEPVTEDVWVYDEADNVMKLRKCTWTPGLYKIFDEILVNAADNKVRDPHGQTTIKVWVDAARGLVRVYNNGEGIPVQRHREHDLWVPEMIFGHLLTSSNYDDTEAKVTGGRNGFGAKLTNVFSTRFEVETVHSRSRKKFFMRWRNNMLENEEAVITPCDGPDYTVVTFYPDFEKFNLEGFTEDMVLIMQRRVYDIAGCTDKSLCCYLNDTRIACRSFPEYVDLYPT-
Q4Q836/12-252              KTQHDHILTRPDMYIGTLEPVTDDIWVYDDAENSMKQRKCTWTPGLYKIFDEILVNAADNKVRDPIGQTVIRVWM--TESYVRVYNNGEGIPIQKHREHDLWVPEMIFGHLLTSSNYDDEEAKVTGGRNGFGAKLTNVFSKQFEVETVHSRSRKKFYMKWTNNMLQHDDPVIVPCDSADYTMVTFYPDFALFHVDKFTEDMLLMMKRRVYDIAGCTDKTLKCFLNDERIACTTFPEYVDLYPT-
A0A0N0DZD8/12-253          KTQHEHILTRPDMYIGTIEPVTDDMWVYDNAENIMKQRKCTWIPGLYKIFDEILVNAADNKVRDPLGQTIIRVWM--TDEYVRVYNNGEGIPIQKHRDHDLWVPEMIFGHLLTSSNYNDAEAKVTGGRNGFGAKLTNVFSKQFEVETVHGRSRKKFYMKWTNNMLQHDDAVIVPCDSADYTMVTFYPDFDRFHVAKFTEDMLLMMKRRVYDVAGCTDKTLKCFLNDERIACTTFPEYVDLYPTM
A0A0N1HUJ9/12-252          KTQHEHILTRPDMYIGTIEPVTDDIWVYDDAESIMKQRKCTWTPGLYKIFDEILVNAADNKVRDPLGQTIIRVWM--TDEYVRVYNNGEGIPIQKHREHDLWVPEMIFGHLLTSSNYNDEEAKVTGGRNGFGAKLTNVFSKQFEVETVHGRSRKKFYMKWTNNMLQHDPPVIVPCDSADYTMVTFYPDFERFHVEKFSEDMLLLMKRRVYDVAGCTDKTLKCFINDERIACTTFPEYVDLYPT-
A4HGT2/12-253              KTQHEHILTRPDMYIGTIEPVTDDIWVYDDAENIMKQRKCTWTPGLYKIFDEILVNAADNKVRDPLGQTVIRVWM--TEDYVRVYNNGEGIPIQRHREHDLWVPEMIFGHLLTSSNYDDEEAKVTGGRNGFGAKLTNVFSKQFEVETVHSRSRKKFYMKWTNNMLQHDDPIIVPCESADYTMVTFYPDFARFHVDKFSEDILLMMKRRVYDVAGCTDKTLKCFLNDERIACTTFPEYVDLYPTM
D0A926/13-255              KTQHEHILARPDMYIGTIEPVTEDVWVYDEADNVMKLRKCTWTPGLYKIFDEILVNAADNKVRDPHGQTTIKVWVDAARGLVRVYNNGEGIPVQRHREHDLWVPEMIFGHLLTSSNYDDTEAKVTGGRNGFGAKLTNVFSTRFEVETVHSRSRKKFFMRWRNNMLENEEAVITPCDGPDYTVVTFYPDFEKFNLEGFTEDMVLIMQRRVYDIAGCTDKSLCCYLNDTRIACRSFPEYVDLYPT-
E9BJW5/12-253              KTQHDHILTRPDMYIGTIEPVTDDIWVYDDAENTMKQRKCTWTPGLYKIFDEILVNAADNKVRDPIGQTVIRVWM--TENYVRVYNNGEGIPIQKHREHDLWVPEMIFGHLLTSSNYDDEEAKVTGGRNGFGAKLTNVFSKQFEVETVHSRSRKKFYMKWANNMLQHDDPVIVPCDSADYTMVTFYPDFALFHVDKFSEDMLLMMKRRVYDVAGCTDKTLKCFLNDERIACTTFPEYVDLYPTM
E9B049/12-253              KTQHDHILTRPDMYIGTIEPVTDDIWVYDDAENIMKQHKCTWTPGLYKIFDEILVNAADNKVRDPIGQTVIRVWM--TENYVRVYNNGEGIPIQKHREHDLWVPEMIFGHLLTSSNYDDEEAKVTGGRNGFGAKLTNVFSKQFEVETVHSRSRKKFYMKWTNNMLQHDDPIIVSCDSADYTMVTFYPDFARFHVDKFSEDMLLMMKRRVYDVAGCTDKTLKCFLNDERIACTTFPEYVDLYPTM
A0A088RVC5/12-253          KTQHEHILTRPDMYIGTIEPVTDDIWVYDDAENIMKQRKCTWTPGLYKIFDEILVNAADNKVRDPLGQTVIRVWM--TEDYVRVYNNGEGIPIQRHREHDLWVPEMIFGHLLTSSNYDDEEAKVTGGRNGFGAKLTNVFSKQFEVETVHSRSRKKFYMKWTNNMLQHDDPIIVPCESADYTMVTFYPDFARFHVDKFSEDILLMMKRRVYDVAGCTDKTLKCFLNDERIACTTFPEYVDLYPTM
A4I3V9/12-253              KTQHDHILTRPDMYIGTIEPVTDDIWVYDDAENTMKQRKCTWTPGLYKIFDEILVNAADNKVRDPIGQTVIRVWM--TENYVRVYNNGEGIPIQKHREHDLWVPEMIFGHLLTSSNYDDEEAKVTGGRNGFGAKLTNVFSKQFEVETVHSRSRKKFYMKWANNMLQHDDPVIVPCDSADYTMVTFYPDFALFHVDKFSEDMLLMMKRRVYDVAGCTDKTLKCFLNDERIACTTFPEYVDLYPTM
A0A3Q8II93/12-253          KTQHDHILTRPDMYIGTIEPVTDDIWVYDDAENTMKQRKCTWTPGLYKIFDEILVNAADNKVRDPIGQTVIRVWM--TENYVRVYNNGEGIPIQKHREHDLWVPEMIFGHLLTSSNYDDEEAKVTGGRNGFGAKLTNVFSKQFEVETVHSRSRKKFYMKWANNMLQHDDPVIVPCDSADYTMVTFYPDFALFHVDKFSEDMLLMMKRRVYDVAGCTDKTLKCFLNDERIACTTFPEYVDLYPTM
A0A3P3ZB29/12-253          KTQHEHILTRPDMYIGTIEPVTDDIWVYDDAENIMKQRKCTWTPGLYKIFDEILVNAADNKVRDPLGQTVIRVWM--TEDYVRVYNNGEGIPIQRHREHDLWVPEMIFGHLLTSSNYDDEEAKVTGGRNGFGAKLTNVFSKQFEVETVHSRSRKKFYMKWTNNMLQHDDPIIVPCESADYTMVTFYPDFARFHVDKFSEDILLMMKRRVYDVAGCTDKTLKCFLNDERIACTTFPEYVDLYPTM
#=GC scorecons             9999799969999999989999796999969785995899998999999999999999999999949995979960065459999999999979699899999999999999999997959999999999999999999956999999979999997979499996676679589766999699999995496665959976969699999799999969597899599995699999999992
#=GC scorecons_70          *********************************_**_****************************_***_*****__*___**************************************_********************_*******************_*****_*__**_***__***********__*_*__*_********************_*_*****_****__**********_
#=GC scorecons_80          ********_*************_*_****_*_*_**_****************************_***_*_**_______***********_*_************************_********************__****************_*_****_____**_***__***_*******__*____*_***_*_*_*****_******_*_*****_****__**********_
#=GC scorecons_90          ****_***_*************_*_****_*_*_**_*****_**********************_***_*_**_______***********_*_**********************_*_********************__*******_******_*_*_****______*_**___***_*******__*____*_**__*_*_*****_******_*_*_***_****__**********_
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