# STOCKHOLM 1.0
#=GF ID 3.30.420.10/FF/000104
#=GF DE Werner Syndrome-like exonuclease
#=GF AC 3.30.420.10/FF/000104
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 84.138
#=GS Q9VE86/113-317      AC Q9VE86
#=GS Q9VE86/113-317      OS Drosophila melanogaster
#=GS Q9VE86/113-317      DE Werner Syndrome-like exonuclease
#=GS Q9VE86/113-317      DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; 
#=GS Q9VE86/113-317      DR GO; GO:0000738; GO:0005634; GO:0008310; GO:0008311; GO:0008408; GO:0045950; GO:0048478; 
#=GS B4JF25/88-296       AC B4JF25
#=GS B4JF25/88-296       OS Drosophila grimshawi
#=GS B4JF25/88-296       DE Werner Syndrome-like exonuclease
#=GS B4JF25/88-296       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; grimshawi group; grimshawi subgroup; Drosophila grimshawi; 
#=GS B4JF25/88-296       DR GO; GO:0005634; GO:0008408; GO:0045950; 
#=GS E8NH59/113-317      AC E8NH59
#=GS E8NH59/113-317      OS Drosophila melanogaster
#=GS E8NH59/113-317      DE RE48478p
#=GS E8NH59/113-317      DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; 
#=GS E1JIP3/114-318      AC E1JIP3
#=GS E1JIP3/114-318      OS Drosophila melanogaster
#=GS E1JIP3/114-318      DE WRN exonuclease, isoform B
#=GS E1JIP3/114-318      DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; 
#=GS A7RY54/5-198        AC A7RY54
#=GS A7RY54/5-198        OS Nematostella vectensis
#=GS A7RY54/5-198        DE Predicted protein
#=GS A7RY54/5-198        DR ORG; Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria; Edwardsiidae; Nematostella; Nematostella vectensis; 
#=GS D6W7R8/24-231       AC D6W7R8
#=GS D6W7R8/24-231       OS Tribolium castaneum
#=GS D6W7R8/24-231       DE Werner Syndrome-like exonuclease
#=GS D6W7R8/24-231       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Tenebrionoidea; Tenebrionidae; Tribolium; Tribolium castaneum; 
#=GS Q5TV84/64-271       AC Q5TV84
#=GS Q5TV84/64-271       OS Anopheles gambiae
#=GS Q5TV84/64-271       DE AGAP000530-PA
#=GS Q5TV84/64-271       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles gambiae; 
#=GS B4K934/87-294       AC B4K934
#=GS B4K934/87-294       OS Drosophila mojavensis
#=GS B4K934/87-294       DE Werner Syndrome-like exonuclease
#=GS B4K934/87-294       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Drosophila; repleta group; mulleri subgroup; Drosophila mojavensis; 
#=GS B4K934/87-294       DR GO; GO:0005634; GO:0008408; GO:0045950; 
#=GS B4M401/88-294       AC B4M401
#=GS B4M401/88-294       OS Drosophila virilis
#=GS B4M401/88-294       DE Werner Syndrome-like exonuclease
#=GS B4M401/88-294       DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Drosophila; virilis group; Drosophila virilis; 
#=GS B4M401/88-294       DR GO; GO:0005634; GO:0008408; GO:0045950; 
#=GS B3LWP6/115-320      AC B3LWP6
#=GS B3LWP6/115-320      OS Drosophila ananassae
#=GS B3LWP6/115-320      DE Werner Syndrome-like exonuclease
#=GS B3LWP6/115-320      DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ananassae subgroup; Drosophila ananassae; 
#=GS B3LWP6/115-320      DR GO; GO:0005634; GO:0008408; GO:0045950; 
#=GS B4G5C9/113-319      AC B4G5C9
#=GS B4G5C9/113-319      OS Drosophila persimilis
#=GS B4G5C9/113-319      DE Werner Syndrome-like exonuclease
#=GS B4G5C9/113-319      DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; pseudoobscura subgroup; Drosophila persimilis; 
#=GS B4G5C9/113-319      DR GO; GO:0005634; GO:0008408; GO:0045950; 
#=GS Q299L3/114-320      AC Q299L3
#=GS Q299L3/114-320      OS Drosophila pseudoobscura pseudoobscura
#=GS Q299L3/114-320      DE Werner Syndrome-like exonuclease
#=GS Q299L3/114-320      DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; pseudoobscura subgroup; Drosophila pseudoobscura; Drosophila pseudoobscura pseudoobscura; 
#=GS Q299L3/114-320      DR GO; GO:0005634; GO:0008408; GO:0045950; 
#=GS B4I298/114-318      AC B4I298
#=GS B4I298/114-318      OS Drosophila sechellia
#=GS B4I298/114-318      DE Werner Syndrome-like exonuclease
#=GS B4I298/114-318      DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila sechellia; 
#=GS B4I298/114-318      DR GO; GO:0005634; GO:0008408; GO:0045950; 
#=GS B4QUF6/114-318      AC B4QUF6
#=GS B4QUF6/114-318      OS Drosophila simulans
#=GS B4QUF6/114-318      DE Werner Syndrome-like exonuclease
#=GS B4QUF6/114-318      DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; 
#=GS B4QUF6/114-318      DR GO; GO:0005634; GO:0008408; GO:0045950; 
#=GS B4N9D3/115-321      AC B4N9D3
#=GS B4N9D3/115-321      OS Drosophila willistoni
#=GS B4N9D3/115-321      DE Werner Syndrome-like exonuclease
#=GS B4N9D3/115-321      DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; willistoni group; willistoni subgroup; Drosophila willistoni; 
#=GS B4N9D3/115-321      DR GO; GO:0005634; GO:0008408; GO:0045950; 
#=GS B4PLB3/114-318      AC B4PLB3
#=GS B4PLB3/114-318      OS Drosophila yakuba
#=GS B4PLB3/114-318      DE Werner Syndrome-like exonuclease
#=GS B4PLB3/114-318      DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; 
#=GS B4PLB3/114-318      DR GO; GO:0005634; GO:0008408; GO:0045950; 
#=GS B3NZ68/114-318      AC B3NZ68
#=GS B3NZ68/114-318      OS Drosophila erecta
#=GS B3NZ68/114-318      DE Werner Syndrome-like exonuclease
#=GS B3NZ68/114-318      DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; 
#=GS B3NZ68/114-318      DR GO; GO:0005634; GO:0008408; GO:0045950; 
#=GS A0A3B0K166/109-315  AC A0A3B0K166
#=GS A0A3B0K166/109-315  OS Drosophila guanche
#=GS A0A3B0K166/109-315  DE Uncharacterized protein
#=GS A0A3B0K166/109-315  DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; obscura subgroup; Drosophila guanche; 
#=GS A0A1W4U929/114-318  AC A0A1W4U929
#=GS A0A1W4U929/114-318  OS Drosophila ficusphila
#=GS A0A1W4U929/114-318  DE Werner Syndrome-like exonuclease
#=GS A0A1W4U929/114-318  DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; 
#=GF SQ 19
Q9VE86/113-317              ----EKEKPEKLPFIKYKGAIKYFTESQDIAASADDVLQWVEKQKD-EVVPMAFDMEWPFSFQTGPG--KSAVIQICVDEKCCYIYQLTN----VKKLPAALVALINHPKVRLHGVNIKNDFRKLARDFPEVTAEPLIEKCVDLGLWCNEVCETGGRWSLERLTNFIAKKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYRELERREKV-
B4JF25/88-296               --SPEKEIPKKLPFIKYSGAIKYFTESQEIAASADEVMQWVEKQINMDVVPMAFDMEWPFSFQTGPG--KSSVIQICVDERCCYVYQLSK----LNKIPAALAALINHPKVRLHGVNIKADFRKLERDFPEMSAEPLIEKCVDLGVWCNQVCETGGRWSLERLANFIAKKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYREIEQRETVK
E8NH59/113-317              ----EKEKPEKLPFIKYKGAIKYFTESQDIAASADDVLQWVEKQKD-EVVPMAFDMEWPFSFQTGPG--KSAVIQICVDEKCCYIYQLTN----VKKLPAALVALINHPKVRLHGVNIKNDFRKLARDFPEVTAEPLIEKCVDLGLWCNEVCETGGRWSLERLTNFIAKKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYRELERREKV-
E1JIP3/114-318              ----EKEKPEKLPFIKYKGAIKYFTESQDIAASADDVLQWVEKQKD-EVVPMAFDMEWPFSFQTGPG--KSAVIQICVDEKCCYIYQLTN----VKKLPAALVALINHPKVRLHGVNIKNDFRKLARDFPEVTAEPLIEKCVDLGLWCNEVCETGGRWSLERLTNFIAKKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYRELERREKV-
A7RY54/5-198                ----EVFSDSKLPLLQYRGMMSYSTHKDECNFICDQLISSDNKPV------MGFDMEWRVAFASGGGSRKTSLIQLCSSESTCYLFQLSSMALLLKKPSQLNYTILEDETIVKVGVGINSDVDKISREY-----DVYPRGIVDLSALANTKLKSHENWSLSGLTMHLFKQQLNKDPAIRCSNCEAIPLTREQQLYAAMDAYVSTYITGV--------
D6W7R8/24-231               KKQKEEEEFRNRPPIQFKGKKIYIRDFIECALACDNLIKLADEAA--DVLVLGFDVEWPFSFQTGPG--KAALIQISPDLDTCYLIQISD----LKKLPKGLSVLLAHPKVRITGVNIKNDIRKLSRDFAGFDVEKNIENCIDSGVLANQILPFQQRWSMERLVTFLLKMTISKDNKVRMSKWHVSPLSKEQLDYAATDAYASLVLYNELKKREAQ-
Q5TV84/64-271               -SKQPDLRVEYLPFVSYTGAIEYYTTFQDVAFSCDQMMQWVEQQQEDRPIPIAFDLEWPFSFQTGPG--RTALMQLCAAPDRCLLLQLSC----LQKLPAALLQLLYHPRVLLHGVNVKNDFRKLARDFPAVSADLLIERCVELGQWYNRLHGTTGIWSLARLVEQVLRQRVSKDKRVRMSKWNVLPLSDDQKLYAAIDVYVGQLLYMKLAERQR--
B4K934/87-294               ---PEKEIPEKLPFIKYRGAIKYFTESQEIAASADEVMQWVDQQTHTEIVPMAFDMEWPFSFQTGPG--KSSVIQICVDERCCYVYQLSN----LKKIPAALVALINHPKVRLHGVNIKADFRKLARDFPEVAAEPLIEKCVDLGVWCNEVCETGGRWSLERLANFIAKKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYREIEQREQTK
B4M401/88-294               ---PEKEIPEKLPFIKYRGAIKYYTESHEIAASADEVMQWVEKQTNADVVPLAFDMEWPFSFQTGPG--KSSVIQICVEERCCYVYQLSK----LKRIPAALVALLNHSKVRLHGVNIKADFRKLERDFPEVAAEPLIEKCIDLGVWCNEVCETGGRWSLERLANFIAKKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYRDIEQREKT-
B3LWP6/115-320              ----EKEKPEKLPFIKYKGAIKYYTESQDIAASADDVMQWVEKQKE-DVVPMAFDMEWPFSFQTGPG--KSSVIQICVDEKCCYIYQLTN----LKKLPSALVALINHPKVRLHGVNIKADFRKLQRDFPEVSADALIEKCVDLGVWCNVICQTGGRWSLERLANFICRKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYRDLEQREKTK
B4G5C9/113-319              ---PEKVKPEKLPFIKYRGAIKYFTENQDIAASADDVMQWVDKQTDVDVVPMAFDMEWPFSFQTGPG--KSSVIQICVDEKCCYVYQLTN----LKKLPAALVALINHPKVRLHGVNIKADFRKLQRDFPEVSADALIEKCVDLGVWCNEICETGGRWSLERLANFIAKKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYRDLEQREKQ-
Q299L3/114-320              ---PEKVKPEKLPFIKYRGAIKYFTENQDIAASADDVMQWVDKQTDVDVVPMAFDMEWPFSFQTGPG--KSSVIQICVDEKCCYVYQLTN----LKKLPAALVALINHPKVRLHGVNIKADFRKLQRDFPEVSADALIEKCVDLGVWCNEICETGGRWSLERLANFIAKKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYRDLEQREKQ-
B4I298/114-318              ----EKEKPEKLPFIKYKGAIKYFTESQDIAASADDVLQWVEKQKD-DVVPMAFDMEWPFSFQTGPG--KSSVIQICVDEKCCYIYQLTN----VKKLPAALVALINHPKVRLHGVNIKNDFRKLARDFPEVTAEPLIEKCVDLGLWCNEVCETGGRWSLERLTNFIAKKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYRELERREKV-
B4QUF6/114-318              ----EKEKPEKLPFIKYKGAIKYFTESQDIAASADDVLQWVEKQKD-DVVPMAFDMEWPFSFQTGPG--KSSVIQICVDEKCCYIYQLTN----VKKLPAALVALINHPKVRLHGVNIKNDFRKLARDFPEVTAEPLIEKCVDLGLWCNEVCETGGRWSLERLTNFIAKKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYRELERREKV-
B4N9D3/115-321              ----EKEKPEKLPFIKYKGAIKYYTENHEIAASADDVIQWIDKQTTLDVVPMAFDMEWPFSFQTGPG--KSSVIQVCVDERCCYVYQLSK----LKKLPAALVALLNHPKVRLHGVNIKADFRKLQRDFPEVSADPLIEKCVDLGVWCNEICETGGRWSLERLANFIAKKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYRDLEQREKVK
B4PLB3/114-318              ----EKEKPEKLPFIKYKGAIKYYTENQDIAASADDVLQWVEKQKD-EVVPMAFDMEWPFSFQTGPG--KSAVIQICVDEKCCYIYQLTN----LKKLPAVLVALINHPKVRLHGVNIKNDFRKLARDFPEVSAEPLIEKCVDLGLWCNEVCETGGRWSLERLTNFIAKKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYRELERREKA-
B3NZ68/114-318              ----EKEKPEKLPFIKYKGAIKYYTESQDIAASADDVLQWVEKQKD-EVVPMAFDMEWPFSFQTGPG--KSAVIQICVDEKCCYIYQLTN----LKKLPAVLVALINHSKVRLHGVNIKNDFRKLARDFPEVSAEPLIEKCVDLGVWCNEVCETGGRWSLERLTNFIAKKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYRELERREKA-
A0A3B0K166/109-315          ---PEKVAPEKMPFIKYTGAIKYYTDNQDIAASADDVMQWVNQQTDVDVVPMAFDMEWPFSFQTGPG--KSSVIQICVDEKCCYVYQLSN----LKKLPAALVALINHPKVRLHGVNIKADFRKLERDFPEVSADALIEKCVDLGVWCNEVCETGGRWSLERLANFIAKRAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYRELEQRQKQ-
A0A1W4U929/114-318          ---PEKKKPEKLPFIKYKGAIKYYTENQDIAASADEVLQWVEKQKD-DVVPMAFDMEWPFSFQTGPG--KSAVIQICVDEKCCYIYQLTN----LKKLPAVLVALINHPKVRLHGVNIKNDFRKLARDFPEVTAEPLIEKCVDLGVWCNEVCGTGGRWSLERLTNFIAKKSQDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYRELERREK--
#=GC scorecons              0001743345669665859564947535757465956565566532044457699799677967969008566896755545975597640000778675564576576675559978759669749785443574567567877455944445465998579555648545595567969776769955695599969696655764554365310
#=GC scorecons_70           ____*_____***_*_*_*___*_*___*_*___*_______*________****************__*__*****_____**__**______***_*__*__**_*_**___*****_*_***_***_____*__**_*****___*________***_**___*_*____*__************___*__*********__**__________
#=GC scorecons_80           ____*_______*___*_*___*_*_________*__________________**_**__**_**_*__*___**_*_____**__**______***_*_____*_____*___**_**_*__**_***____________****___*________***__*_____*____*___**_***_*_**___*__***_*_*________________
#=GC scorecons_90           ____________*___*_*___*___________*__________________**_**___*__*_*__*___**_______*___*_________*_________________**_*__*__*__*_______________*_____*________**___*__________*____*_*_____**___*__***_*_*________________
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