The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 2: Arp2/3 complex 34 kDa subunit

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
35 O15144 (/IPI) O15144 (/IPI) O15144 (/IPI) O15144 (/IPI) O15144 (/IPI) O15144 (/IPI) O15144 (/IPI) O15144 (/IPI) O15144 (/IPI) O15144 (/IPI)
(25 more)
Structural constituent of cytoskeleton GO:0005200
The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.
33 O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA)
(23 more)
Structural constituent of cytoskeleton GO:0005200
The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.
33 O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS)
(23 more)
Structural constituent of cytoskeleton GO:0005200
The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.
4 Q9VIM5 (/ISS) Q9VIM5 (/ISS) Q9VIM5 (/ISS) Q9VIM5 (/ISS)
Structural constituent of cytoskeleton GO:0005200
The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.
1 Q9CVB6 (/ISO)
Kinesin binding GO:0019894
Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.
1 P85970 (/IDA)
Glutamate receptor binding GO:0035254
Interacting selectively and non-covalently with a glutamate receptor.
1 P85970 (/IPI)
Glutamate receptor binding GO:0035254
Interacting selectively and non-covalently with a glutamate receptor.
1 Q9CVB6 (/ISO)
AP-1 adaptor complex binding GO:0035650
Interacting selectively and non-covalently with the AP-1 adaptor complex. The AP-1 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).
1 P85970 (/IDA)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
1 P85970 (/IPI)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
1 Q9CVB6 (/ISO)
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
1 P85970 (/IPI)
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
1 Q9CVB6 (/ISO)
Arp2/3 complex binding GO:0071933
Interacting selectively and non-covalently with an Arp2/3 complex, a protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5).
1 P85970 (/IDA)

There are 42 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of lamellipodium assembly GO:0010592
Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
34 O15144 (/IMP) O15144 (/IMP) O15144 (/IMP) O15144 (/IMP) O15144 (/IMP) O15144 (/IMP) O15144 (/IMP) O15144 (/IMP) O15144 (/IMP) O15144 (/IMP)
(24 more)
Arp2/3 complex-mediated actin nucleation GO:0034314
The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins.
33 O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA)
(23 more)
Fc-gamma receptor signaling pathway involved in phagocytosis GO:0038096
An Fc-gamma receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.
33 O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS)
(23 more)
Ephrin receptor signaling pathway GO:0048013
The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin.
33 O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS)
(23 more)
Membrane organization GO:0061024
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
33 O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS)
(23 more)
Actin polymerization-dependent cell motility GO:0070358
A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell.
33 O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS)
(23 more)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
4 Q9VIM5 (/IMP) Q9VIM5 (/IMP) Q9VIM5 (/IMP) Q9VIM5 (/IMP)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
4 Q9VIM5 (/IMP) Q9VIM5 (/IMP) Q9VIM5 (/IMP) Q9VIM5 (/IMP)
Cell projection assembly GO:0030031
Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.
4 Q9VIM5 (/IMP) Q9VIM5 (/IMP) Q9VIM5 (/IMP) Q9VIM5 (/IMP)
Cortical actin cytoskeleton organization GO:0030866
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of actin-based cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane.
4 Q9VIM5 (/IMP) Q9VIM5 (/IMP) Q9VIM5 (/IMP) Q9VIM5 (/IMP)
Arp2/3 complex-mediated actin nucleation GO:0034314
The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins.
4 Q9VIM5 (/ISS) Q9VIM5 (/ISS) Q9VIM5 (/ISS) Q9VIM5 (/ISS)
Positive regulation of lamellipodium assembly GO:0010592
Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
1 Q9CVB6 (/ISO)
Epithelial cell migration GO:0010631
The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.
1 Q8WTM6 (/IMP)
Positive regulation of smooth muscle cell migration GO:0014911
Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.
1 P85970 (/IMP)
Positive regulation of smooth muscle cell migration GO:0014911
Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.
1 Q9CVB6 (/ISO)
Morphogenesis of embryonic epithelium GO:0016331
The process in which the anatomical structures of embryonic epithelia are generated and organized.
1 Q8WTM6 (/IMP)
Positive regulation of actin filament polymerization GO:0030838
Any process that activates or increases the frequency, rate or extent of actin polymerization.
1 Q9CVB6 (/IDA)
Response to silicon dioxide GO:0034021
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.
1 P85970 (/IEP)
Arp2/3 complex-mediated actin nucleation GO:0034314
The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins.
1 Q9CVB6 (/ISO)
Cellular response to platelet-derived growth factor stimulus GO:0036120
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.
1 P85970 (/IDA)
Cellular response to platelet-derived growth factor stimulus GO:0036120
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.
1 Q9CVB6 (/ISO)
Positive regulation of filopodium assembly GO:0051491
Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
1 P85970 (/IMP)
Positive regulation of filopodium assembly GO:0051491
Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
1 Q9CVB6 (/ISO)
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
1 P85970 (/IEP)
Protein kinase C signaling GO:0070528
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
1 P85970 (/IDA)
Protein kinase C signaling GO:0070528
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
1 Q9CVB6 (/ISO)
Cellular response to epidermal growth factor stimulus GO:0071364
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
1 P85970 (/IMP)
Cellular response to epidermal growth factor stimulus GO:0071364
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
1 Q9CVB6 (/ISO)
Positive regulation of podosome assembly GO:0071803
Any process that activates or increases the rate or extent of podosome assembly.
1 P85970 (/IMP)
Positive regulation of podosome assembly GO:0071803
Any process that activates or increases the rate or extent of podosome assembly.
1 Q9CVB6 (/ISO)
Cellular response to rapamycin GO:0072752
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus.
1 P85970 (/IDA)
Cellular response to rapamycin GO:0072752
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus.
1 Q9CVB6 (/ISO)
Positive regulation of protein targeting to membrane GO:0090314
Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
1 P85970 (/IMP)
Positive regulation of protein targeting to membrane GO:0090314
Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
1 Q9CVB6 (/ISO)
Positive regulation of substrate adhesion-dependent cell spreading GO:1900026
Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.
1 Q9CVB6 (/IMP)
Positive regulation of invadopodium assembly GO:1905926
Any process that activates or increases the frequency, rate or extent of invadopodium assembly.
1 P85970 (/IMP)
Positive regulation of invadopodium assembly GO:1905926
Any process that activates or increases the frequency, rate or extent of invadopodium assembly.
1 Q9CVB6 (/ISO)
Cellular response to nerve growth factor stimulus GO:1990090
A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
1 P85970 (/IEP)
Positive regulation of actin cytoskeleton reorganization GO:2000251
Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization.
1 P85970 (/IMP)
Positive regulation of actin cytoskeleton reorganization GO:2000251
Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization.
1 Q9CVB6 (/ISO)
Positive regulation of barbed-end actin filament capping GO:2000814
Any process that activates or increases the frequency, rate or extent of barbed-end actin filament capping.
1 P85970 (/IMP)
Positive regulation of barbed-end actin filament capping GO:2000814
Any process that activates or increases the frequency, rate or extent of barbed-end actin filament capping.
1 Q9CVB6 (/ISO)

There are 63 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
71 O15144 (/ISS) O15144 (/ISS) O15144 (/ISS) O15144 (/ISS) O15144 (/ISS) O15144 (/ISS) O15144 (/ISS) O15144 (/ISS) O15144 (/ISS) O15144 (/ISS)
(61 more)
Site of double-strand break GO:0035861
A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.
71 O15144 (/ISS) O15144 (/ISS) O15144 (/ISS) O15144 (/ISS) O15144 (/ISS) O15144 (/ISS) O15144 (/ISS) O15144 (/ISS) O15144 (/ISS) O15144 (/ISS)
(61 more)
Arp2/3 protein complex GO:0005885
A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments.
42 P85970 (/ISS) Q0IH88 (/ISS) Q3MHR7 (/ISS) Q3MHR7 (/ISS) Q5R5Z5 (/ISS) Q5R5Z5 (/ISS) Q5R5Z5 (/ISS) Q5R5Z5 (/ISS) Q5R5Z5 (/ISS) Q5R5Z5 (/ISS)
(32 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
35 O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS)
(25 more)
Arp2/3 protein complex GO:0005885
A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments.
34 O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA)
(24 more)
Arp2/3 protein complex GO:0005885
A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments.
34 O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS)
(24 more)
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
34 O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA) O15144 (/IDA)
(24 more)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
33 O15144 (/HDA) O15144 (/HDA) O15144 (/HDA) O15144 (/HDA) O15144 (/HDA) O15144 (/HDA) O15144 (/HDA) O15144 (/HDA) O15144 (/HDA) O15144 (/HDA)
(23 more)
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
33 O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS) O15144 (/TAS)
(23 more)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
33 O15144 (/HDA) O15144 (/HDA) O15144 (/HDA) O15144 (/HDA) O15144 (/HDA) O15144 (/HDA) O15144 (/HDA) O15144 (/HDA) O15144 (/HDA) O15144 (/HDA)
(23 more)
Apical cortex GO:0045179
The region that lies just beneath the plasma membrane on the apical edge of a cell.
4 Q9VIM5 (/HDA) Q9VIM5 (/HDA) Q9VIM5 (/HDA) Q9VIM5 (/HDA)
Cell leading edge GO:0031252
The area of a motile cell closest to the direction of movement.
2 P85970 (/IDA) Q9CVB6 (/IDA)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
2 P85970 (/IDA) Q9CVB6 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q6IRB1 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P85970 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9CVB6 (/ISO)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
1 Q9CVB6 (/IDA)
Arp2/3 protein complex GO:0005885
A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments.
1 Q9CVB6 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9CVB6 (/IDA)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
1 Q9CVB6 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 P85970 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 Q9CVB6 (/ISO)
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
1 Q9CVB6 (/ISO)
Secretory granule GO:0030141
A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
1 P85970 (/IDA)
Secretory granule GO:0030141
A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
1 Q9CVB6 (/ISO)
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
1 P85970 (/IDA)
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
1 Q9CVB6 (/ISO)
Cell leading edge GO:0031252
The area of a motile cell closest to the direction of movement.
1 Q9CVB6 (/ISO)
Filamentous actin GO:0031941
A two-stranded helical polymer of the protein actin.
1 P85970 (/IDA)
Filamentous actin GO:0031941
A two-stranded helical polymer of the protein actin.
1 Q9CVB6 (/ISO)
Ruffle membrane GO:0032587
The portion of the plasma membrane surrounding a ruffle.
1 P85970 (/IDA)
Ruffle membrane GO:0032587
The portion of the plasma membrane surrounding a ruffle.
1 Q9CVB6 (/ISO)
Site of double-strand break GO:0035861
A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.
1 Q6IRB1 (/IDA)
Muscle cell projection membrane GO:0036195
The portion of the plasma membrane surrounding a muscle cell projection.
1 Q9CVB6 (/IDA)
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
1 P85970 (/IDA)
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
1 Q9CVB6 (/ISO)
Dendritic shaft GO:0043198
Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.
1 P85970 (/IDA)
Dendritic shaft GO:0043198
Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.
1 Q9CVB6 (/ISO)
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
1 P85970 (/IDA)
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
1 Q9CVB6 (/ISO)
Axon terminus GO:0043679
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.
1 P85970 (/IDA)
Axon terminus GO:0043679
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.
1 Q9CVB6 (/ISO)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
1 Q9CVB6 (/EXP)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
1 Q9CVB6 (/ISO)
Podosome core GO:0061825
The F-actin-rich core of an adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell.
1 P85970 (/IDA)
Podosome core GO:0061825
The F-actin-rich core of an adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell.
1 Q9CVB6 (/ISO)
Podosome ring GO:0061826
The ring structure surrounding the podosome core, containing proteins such as vinculin and talin.
1 P85970 (/IDA)
Podosome ring GO:0061826
The ring structure surrounding the podosome core, containing proteins such as vinculin and talin.
1 Q9CVB6 (/ISO)
Concave side of sperm head GO:0061830
The concave part of the late spermatid head or spermatozoon head that forms the ventral portion of the head, particularly in some rodent species.
1 P85970 (/IDA)
Concave side of sperm head GO:0061830
The concave part of the late spermatid head or spermatozoon head that forms the ventral portion of the head, particularly in some rodent species.
1 Q9CVB6 (/ISO)
Actin filament branch point GO:0061834
The part of an actin filament where the structure forks.
1 P85970 (/IDA)
Actin filament branch point GO:0061834
The part of an actin filament where the structure forks.
1 Q9CVB6 (/ISO)
Ventral surface of cell GO:0061835
The surface of a migrating cell that is in contact with the substratum or cell layer.
1 P85970 (/IDA)
Ventral surface of cell GO:0061835
The surface of a migrating cell that is in contact with the substratum or cell layer.
1 Q9CVB6 (/ISO)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 B5DGD5 (/IDA)
Invadopodium GO:0071437
A cell projection that emerges from the ECM-facing surface of a cell, is enriched in actin and associated cytoskeletal proteins, and displays localized proteolytic activity toward the substrate.
1 P85970 (/IDA)
Invadopodium GO:0071437
A cell projection that emerges from the ECM-facing surface of a cell, is enriched in actin and associated cytoskeletal proteins, and displays localized proteolytic activity toward the substrate.
1 Q9CVB6 (/ISO)
Peripheral region of growth cone GO:0090725
The non-central region or periphery of the migrating motile tip of a growing nerve cell axon or dendrite.
1 P85970 (/IDA)
Peripheral region of growth cone GO:0090725
The non-central region or periphery of the migrating motile tip of a growing nerve cell axon or dendrite.
1 Q9CVB6 (/ISO)
Apical dendrite GO:0097440
A dendrite that emerges near the apical pole of a neuron. In bipolar neurons, apical dendrites are located on the opposite side of the soma from the axon.
1 P85970 (/IDA)
Apical dendrite GO:0097440
A dendrite that emerges near the apical pole of a neuron. In bipolar neurons, apical dendrites are located on the opposite side of the soma from the axon.
1 Q9CVB6 (/ISO)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
1 Q9CVB6 (/EXP)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
1 Q9CVB6 (/IDA)