The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 20: Triosephosphate isomerase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Triose-phosphate isomerase activity GO:0004807
Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate.
165 P0A858 (/IDA) P0A858 (/IDA) P0A858 (/IDA) P0A858 (/IDA) P0A858 (/IDA) P0A858 (/IDA) P0A858 (/IDA) P0A858 (/IDA) P0A858 (/IDA) P0A858 (/IDA)
(155 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
165 P0A858 (/IPI) P0A858 (/IPI) P0A858 (/IPI) P0A858 (/IPI) P0A858 (/IPI) P0A858 (/IPI) P0A858 (/IPI) P0A858 (/IPI) P0A858 (/IPI) P0A858 (/IPI)
(155 more)
Triose-phosphate isomerase activity GO:0004807
Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate.
158 P04789 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP)
(148 more)
Triose-phosphate isomerase activity GO:0004807
Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate.
157 P0A858 (/ISA) P0A858 (/ISA) P0A858 (/ISA) P0A858 (/ISA) P0A858 (/ISA) P0A858 (/ISA) P0A858 (/ISA) P0A858 (/ISA) P0A858 (/ISA) P0A858 (/ISA)
(147 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
157 P0A858 (/IPI) P0A858 (/IPI) P0A858 (/IPI) P0A858 (/IPI) P0A858 (/IPI) P0A858 (/IPI) P0A858 (/IPI) P0A858 (/IPI) P0A858 (/IPI) P0A858 (/IPI)
(147 more)
Triose-phosphate isomerase activity GO:0004807
Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate.
4 Q869R8 (/ISS) Q9KNR1 (/ISS) Q9KNR1 (/ISS) Q9KNR1 (/ISS)
Triose-phosphate isomerase activity GO:0004807
Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate.
1 P07669 (/IGI)
Triose-phosphate isomerase activity GO:0004807
Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate.
1 Q4QAP8 (/ISO)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
158 P04789 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP)
(148 more)
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
157 P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP) P0A858 (/IMP)
(147 more)
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
8 P9WG43 (/IDA) P9WG43 (/IDA) P9WG43 (/IDA) P9WG43 (/IDA) P9WG43 (/IDA) P9WG43 (/IDA) P9WG43 (/IDA) P9WG43 (/IDA)
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
8 P9WG43 (/IDA) P9WG43 (/IDA) P9WG43 (/IDA) P9WG43 (/IDA) P9WG43 (/IDA) P9WG43 (/IDA) P9WG43 (/IDA) P9WG43 (/IDA)
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
4 Q869R8 (/ISS) Q9KNR1 (/ISS) Q9KNR1 (/ISS) Q9KNR1 (/ISS)
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
1 P07669 (/IC)
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
1 Q4QAP8 (/ISO)
Canonical glycolysis GO:0061621
The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.
1 P07669 (/IGI)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
166 P07669 (/HDA) P0A858 (/HDA) P0A858 (/HDA) P0A858 (/HDA) P0A858 (/HDA) P0A858 (/HDA) P0A858 (/HDA) P0A858 (/HDA) P0A858 (/HDA) P0A858 (/HDA)
(156 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
157 P0A858 (/IDA) P0A858 (/IDA) P0A858 (/IDA) P0A858 (/IDA) P0A858 (/IDA) P0A858 (/IDA) P0A858 (/IDA) P0A858 (/IDA) P0A858 (/IDA) P0A858 (/IDA)
(147 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
157 P0A858 (/HDA) P0A858 (/HDA) P0A858 (/HDA) P0A858 (/HDA) P0A858 (/HDA) P0A858 (/HDA) P0A858 (/HDA) P0A858 (/HDA) P0A858 (/HDA) P0A858 (/HDA)
(147 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
8 P9WG43 (/HDA) P9WG43 (/HDA) P9WG43 (/HDA) P9WG43 (/HDA) P9WG43 (/HDA) P9WG43 (/HDA) P9WG43 (/HDA) P9WG43 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 P9WG43 (/HDA) P9WG43 (/HDA) P9WG43 (/HDA) P9WG43 (/HDA) P9WG43 (/HDA) P9WG43 (/HDA) P9WG43 (/HDA) P9WG43 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P07669 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P04789 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q4QAP8 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q4QAP8 (/ISO)
Glycosome GO:0020015
A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.
1 P04789 (/IDA)
Glycosome GO:0020015
A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.
1 Q4QAP8 (/ISO)
Glycosome GO:0020015
A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.
1 P04789 (/TAS)