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CATH Superfamily 2.60.40.2880

MmpS1-5, C-terminal soluble domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
MmpS1-5, C-terminal soluble domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: MmpS1-5, C-terminal soluble domain

This superfamily includes the C-terminal soluble domain characterised in MmpS4 from Mycobacterium tuberculosis, but is also present in other transport accessory proteins, including MmpS1-5 PMID:11891304. They are part of an export system required for biosynthesis and secretion of siderophores, and are essential for virulence of Mycobacterium tuberculosis PMID:23431276.

MmpS4 possesses an N-terminal transmembrane (TM) helix and a C-terminal soluble domain.

INTERPRO:IPR008693, PFAM:PF05423,DOI:10.1371/journal.ppat.1003120

GO Diversity

Unique GO annotations
3 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
1008 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 1
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 5
Function
Unique EC:
Unique GO: 3
Taxonomy
Unique Species: 1008