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CATH Superfamily 2.60.40.2480

Periplasmic metal-binding protein Tp34-type

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Periplasmic metal-binding protein Tp34-type
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Periplasmic metal-binding protein Tp34-type

Structural domains comprising this superfamily share the structure of the bacterial periplasmic metal-binding protein Tp34. It is believed that Tp34, together with a group of uncharacterised proteins, are involved in high affinity Fe2+ transport. However, the structural and functional aspects of this group of proteins is yet to be determined.

It has been proposed that Tp34 binds zinc and the iron-sequestering lactoferrin PMID:17192261 and that it has a role in metal ion homeostasis PMID:23042995.

GO Diversity

Unique GO annotations
0 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
1136 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 38
Domain clusters (>95% seq id): 3
Domain clusters (>35% seq id): 2
Unique PDBs: 18
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Function
Unique EC:
Unique GO:
Taxonomy
Unique Species: 1136