The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Immunoglobulins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 302: Down syndrome cell adhesion molecule, isoform D

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Antigen binding GO:0003823
Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
77 A0A0B4K6Q9 (/IDA) A0A0B4K6R4 (/IDA) A0A0B4K6R8 (/IDA) A0A0B4K6S2 (/IDA) A0A0B4K6Y9 (/IDA) A0A0B4K6Z3 (/IDA) A0A0B4K6Z6 (/IDA) A0A0B4K6Z8 (/IDA) A0A0B4K7H7 (/IDA) A0A0B4K7H9 (/IDA)
(67 more)
Axon guidance receptor activity GO:0008046
Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance.
77 A0A0B4K6Q9 (/IMP) A0A0B4K6R4 (/IMP) A0A0B4K6R8 (/IMP) A0A0B4K6S2 (/IMP) A0A0B4K6Y9 (/IMP) A0A0B4K6Z3 (/IMP) A0A0B4K6Z6 (/IMP) A0A0B4K6Z8 (/IMP) A0A0B4K7H7 (/IMP) A0A0B4K7H9 (/IMP)
(67 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
77 A0A0B4K6Q9 (/IPI) A0A0B4K6R4 (/IPI) A0A0B4K6R8 (/IPI) A0A0B4K6S2 (/IPI) A0A0B4K6Y9 (/IPI) A0A0B4K6Z3 (/IPI) A0A0B4K6Z6 (/IPI) A0A0B4K6Z8 (/IPI) A0A0B4K7H7 (/IPI) A0A0B4K7H9 (/IPI)
(67 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
77 A0A0B4K6Q9 (/IPI) A0A0B4K6R4 (/IPI) A0A0B4K6R8 (/IPI) A0A0B4K6S2 (/IPI) A0A0B4K6Y9 (/IPI) A0A0B4K6Z3 (/IPI) A0A0B4K6Z6 (/IPI) A0A0B4K6Z8 (/IPI) A0A0B4K7H7 (/IPI) A0A0B4K7H9 (/IPI)
(67 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
6 B7Z0D9 (/ISS) B7Z0D9 (/ISS) M9PHS6 (/ISS) M9PHS6 (/ISS) Q0E8G9 (/ISS) Q0E8G9 (/ISS)

There are 20 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phagocytosis GO:0006909
A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.
77 A0A0B4K6Q9 (/IMP) A0A0B4K6R4 (/IMP) A0A0B4K6R8 (/IMP) A0A0B4K6S2 (/IMP) A0A0B4K6Y9 (/IMP) A0A0B4K6Z3 (/IMP) A0A0B4K6Z6 (/IMP) A0A0B4K6Z8 (/IMP) A0A0B4K7H7 (/IMP) A0A0B4K7H9 (/IMP)
(67 more)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
77 A0A0B4K6Q9 (/IGI) A0A0B4K6R4 (/IGI) A0A0B4K6R8 (/IGI) A0A0B4K6S2 (/IGI) A0A0B4K6Y9 (/IGI) A0A0B4K6Z3 (/IGI) A0A0B4K6Z6 (/IGI) A0A0B4K6Z8 (/IGI) A0A0B4K7H7 (/IGI) A0A0B4K7H9 (/IGI)
(67 more)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
77 A0A0B4K6Q9 (/IMP) A0A0B4K6R4 (/IMP) A0A0B4K6R8 (/IMP) A0A0B4K6S2 (/IMP) A0A0B4K6Y9 (/IMP) A0A0B4K6Z3 (/IMP) A0A0B4K6Z6 (/IMP) A0A0B4K6Z8 (/IMP) A0A0B4K7H7 (/IMP) A0A0B4K7H9 (/IMP)
(67 more)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
77 A0A0B4K6Q9 (/TAS) A0A0B4K6R4 (/TAS) A0A0B4K6R8 (/TAS) A0A0B4K6S2 (/TAS) A0A0B4K6Y9 (/TAS) A0A0B4K6Z3 (/TAS) A0A0B4K6Z6 (/TAS) A0A0B4K6Z8 (/TAS) A0A0B4K7H7 (/TAS) A0A0B4K7H9 (/TAS)
(67 more)
Axonal fasciculation GO:0007413
The collection of axons into a bundle of rods, known as a fascicle.
77 A0A0B4K6Q9 (/IMP) A0A0B4K6R4 (/IMP) A0A0B4K6R8 (/IMP) A0A0B4K6S2 (/IMP) A0A0B4K6Y9 (/IMP) A0A0B4K6Z3 (/IMP) A0A0B4K6Z6 (/IMP) A0A0B4K6Z8 (/IMP) A0A0B4K7H7 (/IMP) A0A0B4K7H9 (/IMP)
(67 more)
Ventral cord development GO:0007419
The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms.
77 A0A0B4K6Q9 (/IGI) A0A0B4K6R4 (/IGI) A0A0B4K6R8 (/IGI) A0A0B4K6S2 (/IGI) A0A0B4K6Y9 (/IGI) A0A0B4K6Z3 (/IGI) A0A0B4K6Z6 (/IGI) A0A0B4K6Z8 (/IGI) A0A0B4K7H7 (/IGI) A0A0B4K7H9 (/IGI)
(67 more)
Peripheral nervous system development GO:0007422
The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.
77 A0A0B4K6Q9 (/IMP) A0A0B4K6R4 (/IMP) A0A0B4K6R8 (/IMP) A0A0B4K6S2 (/IMP) A0A0B4K6Y9 (/IMP) A0A0B4K6Z3 (/IMP) A0A0B4K6Z6 (/IMP) A0A0B4K6Z8 (/IMP) A0A0B4K7H7 (/IMP) A0A0B4K7H9 (/IMP)
(67 more)
Mushroom body development GO:0016319
The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.
77 A0A0B4K6Q9 (/IMP) A0A0B4K6R4 (/IMP) A0A0B4K6R8 (/IMP) A0A0B4K6S2 (/IMP) A0A0B4K6Y9 (/IMP) A0A0B4K6Z3 (/IMP) A0A0B4K6Z6 (/IMP) A0A0B4K6Z8 (/IMP) A0A0B4K7H7 (/IMP) A0A0B4K7H9 (/IMP)
(67 more)
Central nervous system morphogenesis GO:0021551
The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
77 A0A0B4K6Q9 (/IMP) A0A0B4K6R4 (/IMP) A0A0B4K6R8 (/IMP) A0A0B4K6S2 (/IMP) A0A0B4K6Y9 (/IMP) A0A0B4K6Z3 (/IMP) A0A0B4K6Z6 (/IMP) A0A0B4K6Z8 (/IMP) A0A0B4K7H7 (/IMP) A0A0B4K7H9 (/IMP)
(67 more)
Detection of molecule of bacterial origin GO:0032490
The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal.
77 A0A0B4K6Q9 (/IDA) A0A0B4K6R4 (/IDA) A0A0B4K6R8 (/IDA) A0A0B4K6S2 (/IDA) A0A0B4K6Y9 (/IDA) A0A0B4K6Z3 (/IDA) A0A0B4K6Z6 (/IDA) A0A0B4K6Z8 (/IDA) A0A0B4K7H7 (/IDA) A0A0B4K7H9 (/IDA)
(67 more)
Neuron development GO:0048666
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
77 A0A0B4K6Q9 (/IMP) A0A0B4K6R4 (/IMP) A0A0B4K6R8 (/IMP) A0A0B4K6S2 (/IMP) A0A0B4K6Y9 (/IMP) A0A0B4K6Z3 (/IMP) A0A0B4K6Z6 (/IMP) A0A0B4K6Z8 (/IMP) A0A0B4K7H7 (/IMP) A0A0B4K7H9 (/IMP)
(67 more)
Regulation of dendrite morphogenesis GO:0048814
Any process that modulates the frequency, rate or extent of dendrite morphogenesis.
77 A0A0B4K6Q9 (/IGI) A0A0B4K6R4 (/IGI) A0A0B4K6R8 (/IGI) A0A0B4K6S2 (/IGI) A0A0B4K6Y9 (/IGI) A0A0B4K6Z3 (/IGI) A0A0B4K6Z6 (/IGI) A0A0B4K6Z8 (/IGI) A0A0B4K7H7 (/IGI) A0A0B4K7H9 (/IGI)
(67 more)
Regulation of dendrite morphogenesis GO:0048814
Any process that modulates the frequency, rate or extent of dendrite morphogenesis.
77 A0A0B4K6Q9 (/IMP) A0A0B4K6R4 (/IMP) A0A0B4K6R8 (/IMP) A0A0B4K6S2 (/IMP) A0A0B4K6Y9 (/IMP) A0A0B4K6Z3 (/IMP) A0A0B4K6Z6 (/IMP) A0A0B4K6Z8 (/IMP) A0A0B4K7H7 (/IMP) A0A0B4K7H9 (/IMP)
(67 more)
Axon extension involved in axon guidance GO:0048846
The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues.
77 A0A0B4K6Q9 (/IMP) A0A0B4K6R4 (/IMP) A0A0B4K6R8 (/IMP) A0A0B4K6S2 (/IMP) A0A0B4K6Y9 (/IMP) A0A0B4K6Z3 (/IMP) A0A0B4K6Z6 (/IMP) A0A0B4K6Z8 (/IMP) A0A0B4K7H7 (/IMP) A0A0B4K7H9 (/IMP)
(67 more)
Regulation of axonogenesis GO:0050770
Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.
77 A0A0B4K6Q9 (/IMP) A0A0B4K6R4 (/IMP) A0A0B4K6R8 (/IMP) A0A0B4K6S2 (/IMP) A0A0B4K6Y9 (/IMP) A0A0B4K6Z3 (/IMP) A0A0B4K6Z6 (/IMP) A0A0B4K6Z8 (/IMP) A0A0B4K7H7 (/IMP) A0A0B4K7H9 (/IMP)
(67 more)
Detection of mechanical stimulus involved in sensory perception of touch GO:0050976
The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal.
77 A0A0B4K6Q9 (/IGI) A0A0B4K6R4 (/IGI) A0A0B4K6R8 (/IGI) A0A0B4K6S2 (/IGI) A0A0B4K6Y9 (/IGI) A0A0B4K6Z3 (/IGI) A0A0B4K6Z6 (/IGI) A0A0B4K6Z8 (/IGI) A0A0B4K7H7 (/IGI) A0A0B4K7H9 (/IGI)
(67 more)
Dendrite self-avoidance GO:0070593
The process in which dendrites recognize and avoid contact with sister dendrites from the same cell.
77 A0A0B4K6Q9 (/IDA) A0A0B4K6R4 (/IDA) A0A0B4K6R8 (/IDA) A0A0B4K6S2 (/IDA) A0A0B4K6Y9 (/IDA) A0A0B4K6Z3 (/IDA) A0A0B4K6Z6 (/IDA) A0A0B4K6Z8 (/IDA) A0A0B4K7H7 (/IDA) A0A0B4K7H9 (/IDA)
(67 more)
Dendrite self-avoidance GO:0070593
The process in which dendrites recognize and avoid contact with sister dendrites from the same cell.
77 A0A0B4K6Q9 (/IMP) A0A0B4K6R4 (/IMP) A0A0B4K6R8 (/IMP) A0A0B4K6S2 (/IMP) A0A0B4K6Y9 (/IMP) A0A0B4K6Z3 (/IMP) A0A0B4K6Z6 (/IMP) A0A0B4K6Z8 (/IMP) A0A0B4K7H7 (/IMP) A0A0B4K7H9 (/IMP)
(67 more)
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
6 B7Z0D9 (/ISS) B7Z0D9 (/ISS) M9PHS6 (/ISS) M9PHS6 (/ISS) Q0E8G9 (/ISS) Q0E8G9 (/ISS)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
1 A0A0B4K823 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
83 A0A0B4K6Q9 (/ISM) A0A0B4K6R4 (/ISM) A0A0B4K6R8 (/ISM) A0A0B4K6S2 (/ISM) A0A0B4K6Y9 (/ISM) A0A0B4K6Z3 (/ISM) A0A0B4K6Z6 (/ISM) A0A0B4K6Z8 (/ISM) A0A0B4K7H7 (/ISM) A0A0B4K7H9 (/ISM)
(73 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
77 A0A0B4K6Q9 (/ISS) A0A0B4K6R4 (/ISS) A0A0B4K6R8 (/ISS) A0A0B4K6S2 (/ISS) A0A0B4K6Y9 (/ISS) A0A0B4K6Z3 (/ISS) A0A0B4K6Z6 (/ISS) A0A0B4K6Z8 (/ISS) A0A0B4K7H7 (/ISS) A0A0B4K7H9 (/ISS)
(67 more)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
77 A0A0B4K6Q9 (/IDA) A0A0B4K6R4 (/IDA) A0A0B4K6R8 (/IDA) A0A0B4K6S2 (/IDA) A0A0B4K6Y9 (/IDA) A0A0B4K6Z3 (/IDA) A0A0B4K6Z6 (/IDA) A0A0B4K6Z8 (/IDA) A0A0B4K7H7 (/IDA) A0A0B4K7H9 (/IDA)
(67 more)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
77 A0A0B4K6Q9 (/IDA) A0A0B4K6R4 (/IDA) A0A0B4K6R8 (/IDA) A0A0B4K6S2 (/IDA) A0A0B4K6Y9 (/IDA) A0A0B4K6Z3 (/IDA) A0A0B4K6Z6 (/IDA) A0A0B4K6Z8 (/IDA) A0A0B4K7H7 (/IDA) A0A0B4K7H9 (/IDA)
(67 more)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
77 A0A0B4K6Q9 (/IDA) A0A0B4K6R4 (/IDA) A0A0B4K6R8 (/IDA) A0A0B4K6S2 (/IDA) A0A0B4K6Y9 (/IDA) A0A0B4K6Z3 (/IDA) A0A0B4K6Z6 (/IDA) A0A0B4K6Z8 (/IDA) A0A0B4K7H7 (/IDA) A0A0B4K7H9 (/IDA)
(67 more)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
77 A0A0B4K6Q9 (/IDA) A0A0B4K6R4 (/IDA) A0A0B4K6R8 (/IDA) A0A0B4K6S2 (/IDA) A0A0B4K6Y9 (/IDA) A0A0B4K6Z3 (/IDA) A0A0B4K6Z6 (/IDA) A0A0B4K6Z8 (/IDA) A0A0B4K7H7 (/IDA) A0A0B4K7H9 (/IDA)
(67 more)