# STOCKHOLM 1.0 #=GF ID 2.40.70.10/FF/000100 #=GF DE Cathepsin E-like protease #=GF AC 2.40.70.10/FF/000100 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 90.551 #=GS Q9VQ14/258-374 AC Q9VQ14 #=GS Q9VQ14/258-374 OS Drosophila melanogaster #=GS Q9VQ14/258-374 DE MIP16848p #=GS Q9VQ14/258-374 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS Q9VQ14/258-374 DR GO; GO:0007306; GO:0042600; #=GS Q9VLK3/246-353 AC Q9VLK3 #=GS Q9VLK3/246-353 OS Drosophila melanogaster #=GS Q9VLK3/246-353 DE Beta-site APP-cleaving enzyme, isoform A #=GS Q9VLK3/246-353 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS Q9VLK3/246-353 DR GO; GO:1902944; #=GS A0A139WER9/265-390 AC A0A139WER9 #=GS A0A139WER9/265-390 OS Tribolium castaneum #=GS A0A139WER9/265-390 DE Lysosomal aspartic protease-like Protein #=GS A0A139WER9/265-390 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Tenebrionoidea; Tenebrionidae; Tribolium; Tribolium castaneum; #=GS B3SBG1/246-364 AC B3SBG1 #=GS B3SBG1/246-364 OS Trichoplax adhaerens #=GS B3SBG1/246-364 DE Uncharacterized protein #=GS B3SBG1/246-364 DR ORG; Eukaryota; Metazoa; Placozoa; Trichoplacidae; Trichoplax; Trichoplax adhaerens; #=GS B3RK42/218-337 AC B3RK42 #=GS B3RK42/218-337 OS Trichoplax adhaerens #=GS B3RK42/218-337 DE Uncharacterized protein #=GS B3RK42/218-337 DR ORG; Eukaryota; Metazoa; Placozoa; Trichoplacidae; Trichoplax; Trichoplax adhaerens; #=GS H3GYP8/265-392 AC H3GYP8 #=GS H3GYP8/265-392 OS Phytophthora ramorum #=GS H3GYP8/265-392 DE Uncharacterized protein #=GS H3GYP8/265-392 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora ramorum; #=GS H9GJA6/255-376 AC H9GJA6 #=GS H9GJA6/255-376 OS Anolis carolinensis #=GS H9GJA6/255-376 DE Uncharacterized protein #=GS H9GJA6/255-376 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Lepidosauria; Squamata; Iguania; Dactyloidae; Anolis; Anolis carolinensis; #=GS W5NH59/259-381 AC W5NH59 #=GS W5NH59/259-381 OS Lepisosteus oculatus #=GS W5NH59/259-381 DE Uncharacterized protein #=GS W5NH59/259-381 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Holostei; Semionotiformes; Lepisosteidae; Lepisosteus; Lepisosteus oculatus; #=GS G3S939/209-323 AC G3S939 #=GS G3S939/209-323 OS Gorilla gorilla gorilla #=GS G3S939/209-323 DE Uncharacterized protein #=GS G3S939/209-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Gorilla; Gorilla gorilla; Gorilla gorilla gorilla; #=GS F7EUW5/213-326 AC F7EUW5 #=GS F7EUW5/213-326 OS Ornithorhynchus anatinus #=GS F7EUW5/213-326 DE Uncharacterized protein #=GS F7EUW5/213-326 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus; Ornithorhynchus anatinus; #=GS H2MSN1/261-383 AC H2MSN1 #=GS H2MSN1/261-383 OS Oryzias latipes #=GS H2MSN1/261-383 DE Cathepsin E-like protease #=GS H2MSN1/261-383 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Euteleosteomorpha; Atherinomorphae; Beloniformes; Adrianichthyoidei; Adrianichthyidae; Oryziinae; Oryzias; Oryzias latipes; #=GS B4Q752/258-374 AC B4Q752 #=GS B4Q752/258-374 OS Drosophila simulans #=GS B4Q752/258-374 DE GD23101 #=GS B4Q752/258-374 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GS B4HYN5/246-353 AC B4HYN5 #=GS B4HYN5/246-353 OS Drosophila sechellia #=GS B4HYN5/246-353 DE GM12869 #=GS B4HYN5/246-353 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila sechellia; #=GS A0A0J9QYU8/246-353 AC A0A0J9QYU8 #=GS A0A0J9QYU8/246-353 OS Drosophila simulans #=GS A0A0J9QYU8/246-353 DE Uncharacterized protein #=GS A0A0J9QYU8/246-353 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GS A0A3P9LSB8/261-383 AC A0A3P9LSB8 #=GS A0A3P9LSB8/261-383 OS Oryzias latipes #=GS A0A3P9LSB8/261-383 DE Nothepsin #=GS A0A3P9LSB8/261-383 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Euteleosteomorpha; Atherinomorphae; Beloniformes; Adrianichthyoidei; Adrianichthyidae; Oryziinae; Oryzias; Oryzias latipes; #=GS A0A3P9H637/261-383 AC A0A3P9H637 #=GS A0A3P9H637/261-383 OS Oryzias latipes #=GS A0A3P9H637/261-383 DE Nothepsin #=GS A0A3P9H637/261-383 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Euteleosteomorpha; Atherinomorphae; Beloniformes; Adrianichthyoidei; Adrianichthyidae; Oryziinae; Oryzias; Oryzias latipes; #=GF SQ 16 Q9VQ14/258-374 YWSFKLDFIAV-------------HGKGSRSSRTGNKAIMDTGTSLIVGPVLEVLYINKDIGAEHNKTYNLYTVACE--SIPQLPIIVFGIAGKE-FFVKPHTYVIRY----DNFCFSAFMDML----GLQYWILGDAFMR Q9VLK3/246-353 YWQFTMAGSSI-------------DGY--SLC-DDCQAIADTGTSLIVAPYNAYITLSEILNVG-----EDGYLDCS--SVSSLPDVTFNIGGTN-FVLKPSAYIIQS----DGNCMSAFEYM-----GTDFWILGDVFIG A0A139WER9/265-390 YWQFQMDQVVVK-VSK--------DNN-VVVCEKGCKAIVDTSSNAIVGPQADIAQIHDAINANEFF-LHRYTVNCD--TVNKLPKIDFMLGGTN-FTLSGEDYTVKMSYHSVTICLSAFIPAN-TIQEQDRWILGGAFLA B3SBG1/246-364 SWIIKVDSGTV-------------NRG-VKFCTHGCTAIIETGTSLIFGPSKDIQRIQHAIGAQKIG--GQNFIDCT--RIKSLPKITFTIDKIR-YTLDPEHYVHQYTLKGNKHCISGFLELE---EEEDTWIFGDVFLR B3RK42/218-337 LWQFAIDGGKI-------------ASG-ESFCIGGCQAIADTGSSLIFGPPKDIIPILYAIGADPRD--PNGVVDCK--TISSLPIITFTINRVD-YSLSGEQYILQLTQDGRKECFSGFAFYN--GPQNSVLTLGDIFLH H3GYP8/265-392 YWTIKMNNFSIQPVGDDNNNNGETDVT-ANMCDPFCYAIVDTGTSLISVPAGQYDEVVSKITRG----LDCDGIDCDGVAVKDFPVLHFGMEPDNVFLLQPQDYVQCS---GWGQCKLQFQST-----TDEWWILGDVFIK H9GJA6/255-376 YWQIQLDNIQV-------------GGT-IAFCAEGCQAIVDTGTSLITGPSDDIKQMQNLIGAQPVD--GEYAVECS--NLSMMPSVTFTLNGIP-YSLTPEAYTLMENSDGMQLCSSGFQALNMQTPEGPLWILGDVFIG W5NH59/259-381 YWQIKVDNVKI-------------QGH-VAFCSTGCQAIVDTGTSLITGPTVDILALQQHIGATPSQ-LGEYLVDCA--RLSSLPLVEFTIHEVV-YKLSANSYVRKETLGGRELCFSGFQAIDIKTSSGPLWILGDVFIS G3S939/209-323 YWQFTVDSVII-------------DGM-VVVCDGGCQAILDTGTSLLVGPGSNILNIQQAIGATAGQ-YNEFDIDCG--RLSSMPTVVFEIHGKK-YPLPPSAYTSQD----QGFCTSGFQGDY----SSQQWILGGVFTR F7EUW5/213-326 YWQIAVDKITV-------------DGE-VVACGGGCQAILDTGTSLMAGPSPDIAGIQYLIGATEGR-NGLYQVDCR--KLQRLPDVVFHISGVK-YPLTATAYTNKN----GGICYSGFEGE-----SGGQWILGVVFIR H2MSN1/261-383 YWQIRMDSVSV-------------QGV-SSLCRRGCEAIVDTGTSLIAGPPREILRLHQLIGATPTH-FGDFVVDCA--RLSSLPHVTFVLGEVE-YTLTSEHYIRKETFSSRELCFTGFMAAEMFSADGPLWILGDVFLT B4Q752/258-374 YWTFKLDFIAV-------------HGKGSRSSRSGNKAIMDTGTSLIVGPVLEVLYINKDIGAKHNKTYNLYTVSCE--SIPQLPIIVFGIAGKE-FFVKPHTYVIRY----DNFCFSAFMDML----GLQYWILGDAFMR B4HYN5/246-353 YWQFTMAGSSI-------------DGY--SLC-DDCQAIADTGTSLIVAPYYAYITLSEILNVG-----EDGYLDCS--SVSSLPDVTFNIGGTN-FVLKPSAYIIQS----DDSCMSAFEYM-----GTDFWILGDVFIG A0A0J9QYU8/246-353 YWQFTMAGSSI-------------DGY--SLC-DDCQAIADTGTSLIVAPYNAYITLSEILNVG-----EDGYLDCS--SVSSLPDVTFNIGGTN-FVLKPSAYIIQS----DGNCMSAFEYM-----GTDFWILGDVFIG A0A3P9LSB8/261-383 YWQIRMDSVSV-------------QGV-SSLCRRGCEAIVDTGTSLIAGPPREILRLHQLIGATPTH-FGDFVVDCA--RLSSLPHVTFVLGEVE-YTLTSEHYIRKETFSSRELCFTGFMAAEIFSADGPLWILGDVFLT A0A3P9H637/261-383 YWQIRMDSVSV-------------QGV-SSLCRRGCEAIVDTGTSLIAGPPREILRLHQLVGATPTH-FGDFVVDCA--RLSSLPHVTFVLGEVE-YTLTSEHYIRKETFSSRELCFTGFMAAEIFSADGPLWILGDVFLT #=GC scorecons 795545634470000000000000452023472367499589878874693245335333756321101433266930045547926493645340737354395343100134393659333100004333888966953 #=GC scorecons_70 **____*___*____________________*___*_**_*******_**__________*_*__________***_______**_*_*_*_____*_*____*___________*_*_*____________*******__ #=GC scorecons_80 **_____________________________*___*_**_*******__*_________________________*_______**___*_______*_*____*___________*___*____________****__*__ #=GC scorecons_90 _*___________________________________**_***_*____*_________________________*________*___*______________*___________*___*_____________***__*__ //