The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Non-homologous end joining protein Ku

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
12 P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA)
(2 more)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of ligase activity GO:0051351
Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
11 P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA)
(1 more)
Double-strand break repair via nonhomologous end joining GO:0006303
The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.
10 P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA) P9WKD9 (/IDA)
Double-strand break repair via nonhomologous end joining GO:0006303
The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.
1 A0R3S7 (/IMP)
Double-strand break repair via nonhomologous end joining GO:0006303
The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.
1 A0R3S7 (/IPI)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.