The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Fumarase/aspartase (Central domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Fumarate hydratase, mitochondrial

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
139 P07954 (/IPI) P07954 (/IPI) P0AC38 (/IPI) P0AC38 (/IPI) P0AC38 (/IPI) P0AC38 (/IPI) P0AC38 (/IPI) P0AC38 (/IPI) P0AC38 (/IPI) P0AC38 (/IPI)
(129 more)
Aspartate ammonia-lyase activity GO:0008797
Catalysis of the reaction: L-aspartate = fumarate + NH3.
133 P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA)
(123 more)
Fumarate hydratase activity GO:0004333
Catalysis of the reaction: (S)-malate = fumarate + H(2)O.
50 P05042 (/IDA) P05042 (/IDA) P05042 (/IDA) P05042 (/IDA) P05042 (/IDA) P05042 (/IDA) P05042 (/IDA) P05042 (/IDA) P05042 (/IDA) P05042 (/IDA)
(40 more)
Fumarate hydratase activity GO:0004333
Catalysis of the reaction: (S)-malate = fumarate + H(2)O.
25 O94552 (/ISS) P55250 (/ISS) P97807 (/ISS) Q48EA6 (/ISS) Q48EA6 (/ISS) Q48EA6 (/ISS) Q48EA6 (/ISS) Q48EA6 (/ISS) Q608E9 (/ISS) Q60HF9 (/ISS)
(15 more)
Aspartate ammonia-lyase activity GO:0008797
Catalysis of the reaction: L-aspartate = fumarate + NH3.
9 Q5LQ33 (/ISS) Q74FX3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS)
Fumarate hydratase activity GO:0004333
Catalysis of the reaction: (S)-malate = fumarate + H(2)O.
3 P14408 (/IMP) Q9FI53 (/IMP) Q9FI53 (/IMP)
Fumarate hydratase activity GO:0004333
Catalysis of the reaction: (S)-malate = fumarate + H(2)O.
3 A0A1D8PKV4 (/NAS) Q5A6L1 (/NAS) Q5A6L1 (/NAS)
Fumarate hydratase activity GO:0004333
Catalysis of the reaction: (S)-malate = fumarate + H(2)O.
2 Q5ASM3 (/RCA) Q5ASM3 (/RCA)
Fumarate hydratase activity GO:0004333
Catalysis of the reaction: (S)-malate = fumarate + H(2)O.
2 P07954 (/TAS) P07954 (/TAS)
Fumarate hydratase activity GO:0004333
Catalysis of the reaction: (S)-malate = fumarate + H(2)O.
1 P97807 (/ISO)
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
1 P97807 (/ISO)

There are 40 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Aspartate metabolic process GO:0006531
The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.
132 P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA)
(122 more)
Cellular amino acid biosynthetic process GO:0008652
The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
132 P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA)
(122 more)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
23 P05042 (/IEP) P05042 (/IEP) P05042 (/IEP) P05042 (/IEP) P05042 (/IEP) P05042 (/IEP) P05042 (/IEP) P05042 (/IEP) P05042 (/IEP) P05042 (/IEP)
(13 more)
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
21 O94552 (/ISS) Q48EA6 (/ISS) Q48EA6 (/ISS) Q48EA6 (/ISS) Q48EA6 (/ISS) Q48EA6 (/ISS) Q608E9 (/ISS) Q87WT2 (/ISS) Q8IRQ5 (/ISS) Q8SXM1 (/ISS)
(11 more)
Fumarate metabolic process GO:0006106
The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.
14 P07954 (/IDA) P07954 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P10173 (/IDA) P14408 (/IDA)
(4 more)
Fumarate metabolic process GO:0006106
The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.
8 P08417 (/IMP) P08417 (/IMP) P08417 (/IMP) P08417 (/IMP) P08417 (/IMP) P08417 (/IMP) Q9FI53 (/IMP) Q9FI53 (/IMP)
Malate metabolic process GO:0006108
The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
8 P07954 (/IDA) P07954 (/IDA) P10173 (/IDA) P14408 (/IDA) P93033 (/IDA) P93033 (/IDA) Q9FI53 (/IDA) Q9FI53 (/IDA)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
7 Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS)
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
6 P08417 (/IMP) P08417 (/IMP) P08417 (/IMP) P08417 (/IMP) P08417 (/IMP) P08417 (/IMP)
Double-strand break repair GO:0006302
The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.
6 P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
6 P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA)
Fumarate metabolic process GO:0006106
The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.
5 O94552 (/ISS) P55250 (/ISS) P97807 (/ISS) Q60HF9 (/ISS) Q7SX99 (/ISS)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
4 P93033 (/IEP) P93033 (/IEP) Q9FI53 (/IEP) Q9FI53 (/IEP)
Protein tetramerization GO:0051262
The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.
4 P93033 (/IDA) P93033 (/IDA) Q9FI53 (/IDA) Q9FI53 (/IDA)
Fumarate metabolic process GO:0006106
The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.
3 P07954 (/TAS) P07954 (/TAS) P14408 (/TAS)
Malate metabolic process GO:0006108
The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
3 P97807 (/ISS) Q60HF9 (/ISS) Q7SX99 (/ISS)
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
3 P07954 (/ISS) P07954 (/ISS) P14408 (/ISS)
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
2 Q5ASM3 (/RCA) Q5ASM3 (/RCA)
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
2 P07954 (/TAS) P07954 (/TAS)
Double-strand break repair GO:0006302
The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.
2 O94552 (/ISS) P55250 (/ISS)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
2 O94552 (/ISS) P55250 (/ISS)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 P93033 (/IDA) P93033 (/IDA)
Cold acclimation GO:0009631
Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures.
2 Q9FI53 (/IMP) Q9FI53 (/IMP)
Regulation of photosynthesis GO:0010109
Any process that modulates the frequency, rate or extent of photosynthesis.
2 Q9FI53 (/IMP) Q9FI53 (/IMP)
Nitrate assimilation GO:0042128
The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances.
2 Q9FI53 (/IMP) Q9FI53 (/IMP)
Pollen tube development GO:0048868
The process whose specific outcome is the progression of a pollen tube over time, from its initial formation to a mature structure.
2 P93033 (/IMP) P93033 (/IMP)
Negative regulation of histone H3-K36 methylation GO:0000415
Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3.
1 P97807 (/ISO)
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
1 P14408 (/IDA)
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
1 P97807 (/ISO)
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
1 A0A1D8PKV4 (/NAS)
Fumarate metabolic process GO:0006106
The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.
1 P97807 (/ISO)
Malate metabolic process GO:0006108
The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
1 P97807 (/ISO)
Aspartate catabolic process GO:0006533
The chemical reactions and pathways resulting in the breakdown of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.
1 Q74FX3 (/ISS)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
1 P97807 (/ISO)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
1 Q54VA2 (/HEP)
Cellular response to iron ion starvation GO:0010106
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions.
1 Q51404 (/IDA)
Positive regulation of plasminogen activation GO:0010756
Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.
1 P44324 (/IDA)
Homeostasis of number of cells within a tissue GO:0048873
Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue.
1 P97807 (/IMP)
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
1 P97807 (/IMP)
Positive regulation of double-strand break repair via nonhomologous end joining GO:2001034
Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining.
1 P97807 (/ISO)

There are 24 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
144 O94552 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA)
(134 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
140 P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA)
(130 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
132 P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA)
(122 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
15 O17214 (/HDA) P07954 (/HDA) P07954 (/HDA) P08417 (/HDA) P08417 (/HDA) P08417 (/HDA) P08417 (/HDA) P08417 (/HDA) P08417 (/HDA) P97807 (/HDA)
(5 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
15 A0A0S2Z4C3 (/IDA) A0A0S2Z4C3 (/IDA) P07954 (/IDA) P07954 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA)
(5 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
11 P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA)
(1 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
11 P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA)
(1 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
11 P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA) P9WN93 (/HDA)
(1 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
9 O94552 (/ISS) P55250 (/ISS) Q54VA2 (/ISS) Q8IRQ5 (/ISS) Q8SXM1 (/ISS) Q9VTI5 (/ISS) Q9W3X5 (/ISS) Q9W3X6 (/ISS) Q9W3X6 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 Q54VA2 (/ISS) Q8IRQ5 (/ISS) Q8SXM1 (/ISS) Q9VTI5 (/ISS) Q9W3X5 (/ISS) Q9W3X6 (/ISS) Q9W3X6 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
6 P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA) P08417 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 O94552 (/ISS) P55250 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P07954 (/TAS) P07954 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 P07954 (/TAS) P07954 (/TAS)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
2 P07954 (/TAS) P07954 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 P07954 (/HDA) P07954 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P97807 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P97807 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 P97807 (/ISO)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
1 O94552 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P97807 (/ISO)
Site of double-strand break GO:0035861
A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.
1 P97807 (/ISO)
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
1 Q54VA2 (/HDA)