# STOCKHOLM 1.0 #=GF ID 1.10.287.70/FF/000296 #=GF DE TWiK family of potassium channels #=GF AC 1.10.287.70/FF/000296 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 88.838 #=GS Q8IG65/71-371 AC Q8IG65 #=GS Q8IG65/71-371 OS Caenorhabditis elegans #=GS Q8IG65/71-371 DE TWiK family of potassium channels #=GS Q8IG65/71-371 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS A7RYH6/39-352 AC A7RYH6 #=GS A7RYH6/39-352 OS Nematostella vectensis #=GS A7RYH6/39-352 DE Predicted protein #=GS A7RYH6/39-352 DR ORG; Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria; Edwardsiidae; Nematostella; Nematostella vectensis; #=GS W4ZC62/21-173_290-390 AC W4ZC62 #=GS W4ZC62/21-173_290-390 OS Strongylocentrotus purpuratus #=GS W4ZC62/21-173_290-390 DE Uncharacterized protein #=GS W4ZC62/21-173_290-390 DR ORG; Eukaryota; Metazoa; Echinodermata; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae; Strongylocentrotus; Strongylocentrotus purpuratus; #=GS C3Y5S5/33-333 AC C3Y5S5 #=GS C3Y5S5/33-333 OS Branchiostoma floridae #=GS C3Y5S5/33-333 DE Uncharacterized protein #=GS C3Y5S5/33-333 DR ORG; Eukaryota; Metazoa; Chordata; Cephalochordata; Branchiostomidae; Branchiostoma; Branchiostoma floridae; #=GS A0A2G5VKA1/54-355 AC A0A2G5VKA1 #=GS A0A2G5VKA1/54-355 OS Caenorhabditis nigoni #=GS A0A2G5VKA1/54-355 DE Uncharacterized protein #=GS A0A2G5VKA1/54-355 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; #=GS A8XG34/88-392 AC A8XG34 #=GS A8XG34/88-392 OS Caenorhabditis briggsae #=GS A8XG34/88-392 DE Protein CBR-TWK-37 #=GS A8XG34/88-392 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis briggsae; #=GS C3Y5S7/157-439 AC C3Y5S7 #=GS C3Y5S7/157-439 OS Branchiostoma floridae #=GS C3Y5S7/157-439 DE Uncharacterized protein #=GS C3Y5S7/157-439 DR ORG; Eukaryota; Metazoa; Chordata; Cephalochordata; Branchiostomidae; Branchiostoma; Branchiostoma floridae; #=GF SQ 7 Q8IG65/71-371 -RKSRAERPKPTKLRTILRKIRKFNT---------IIAFVVLVAYIIGGALLFWQIESRSDMNINEFKRNIRQKSIHIYNSMK-----------GSKCGKLKKADNELNNNCIKEIFDLLY-----ASNPPKHIEEFLDGLAYVITCITTIGYGELVCHTIAGKLVTVAYGIIGIALTLYVLRNNGKITLKICNLTLKIFAICVR---KCGK----------KSAKYKMTVLKAFILLVTFWGFGALAI----AVYEEFVFYDALYFSFSTFSTIGFGDFV------PSGHISGTIICVLHFIDLSLISMVLVLVH--------------HSMENRFMRVLELFDERHATDTLETNMISPGASQ A7RYH6/39-352 ---------TLKCLTWVKKKIKKKGA-----IFP-LFMILVNTIYLAIGGIIFMSLERSPKAKIDT-SKDLIEIFSVLKRSYIGNLSFPDNVSSLDMVGNLTTADLHRFEKLLSKIHVSRA-----LSAKP--QWNILNSIYFCMTVTTTIGYGSLAPVTVPGRVICVIYALLGIPLTLALLAVVGKIVGDYINDTCALVLKWFRHLYPDYEYENMNQNQELGDGQIDAPLWLGLLILFIFTTITAGLC----CWMEGWDFGTSFYFQFVTYLTIGFGDVV------PTSEKYTFVYILLTLLGLSVLSVTLSLIA--------------TNLHHQVQKANFLEKLKQRDISTTA---SVGSGE W4ZC62/21-173_290-390 -TRIEGQR------------------------------------------------ETHKEAEE---KRWLHELITRTIKNVS---TPKINFV-------MTETDYLK-SDVIEDSIDEIVN--RYHPEKRNYKWDMAGGVHFCLTVVSTIGYGLVVPRTQLGRAVCVIYAMIGIPINIIFMAGIGRVIARLIDRTYCMCLRAFRN-CPCYK----------SQPKQDHPVWFVIFFVLIVVSLFTILIWNSGILEDEWTLIDLIYFKFITYSTIGFGDLFINAPKGANHSLSVFIDVVIIVVGMSLVSTVINIL---------------TSSNRCDQALNF----------ATC--------- C3Y5S5/33-333 ----------KEGWTDVKEKRRKKLVLALKESWPHVKLGVILVIYAMFGAVGFWLIEYHHEQAL---VANFTEARSQLLRDMW---NVSQDFT-GDDWEEEMTTLVMRYEHTIVEAYDGGIDPRGVTAGQAELKWDIAGSLFFSVTVFTTIGYGHQTPATVAGRVFCIFYAIFGIPILLLTLGDIGELLAKLLRYIAAVVNSKLR---PNMM----------ESRKDDVPLYGIFTVVFLIMSMGAVVM----MQMEDWTFEQSFYFIFVTFSTIGFGDLV------PHHKMYALGASLYFLLGMSLISTSFSLSQ--------------EEVGRLLRKWDVLKASCKRKMCPCC--------- A0A2G5VKA1/54-355 VKREEKEKPKQSTFKKIRRKIRKFNT---------IIAFVILIAYTCGGAALFWQIESNSDKKLDEYHKNVLQKSKELYKALP-----------PNQCGPLTPNHNEINNKCLKLIYDSLY-----NLNPPRYINTYLDGLAYVLTCITTIGYGQLVCRTIVGKMVTVVYGIIGIALTIYVLRHNGKVALRVCNWVLGLVARCWR---ICGN----------KKVKFRMTVTKSFILLFTFWTLGSLGI----ASYEKFVFWDAIYFSFSTFSTVGFGDLV------PTSHISGAIIFALHFIDLCLLSMVFVLVH--------------QTMENNFMKVLELLDEGYRKHTTELNTGTMNLQS A8XG34/88-392 VKREEKEKPKQTTFKKIRKKIRKFNT---------IIAFIILVAYICGGAALFWQIESNSDKKLDDYHKNVLQKSKELYKALP-----------PNQCGPLKPNHNEINNKCLKLIYESLY-----NLNPPRYINTYLDGLAYVLTCITTIGYGQLVCRTIVGKMVTVVYGIIGIALTIYVLRHNGKVALRVCNWALGLVASCWR---VCGN----------KKVKFRMTVTKSFILLFTFWTLGSLGI----ASYEKFVFWDAIYFSFSTFSTVGFGDLV------PTSHISGVIIFALHFIDLCLLSMVFVLVHVPFREAVIYPIEIQQTMENSFMKVLELLDEGYRKHTT----------- C3Y5S7/157-439 --------------AWCSCSVRNAAFT----VWPHLKIVILNVAYLGFGAWVFCTLECEGQKAR---HPDLPASRHLVLDRLQ---AAVNNTTSFENWTKIADLEMARHEEMVVQARQEFVW--GTNGSSPPYLSDPSRAVFFAAVVVTTIGYGHVTPQTTGGRVFLMFYALFGMPLMLAWLADINRLVGRLLHFLVGKINSVVR---PELP----------ADKARRVPVWVIVLLLVIYLLVGAGVL----CFWEDWTFMDSLYYTYITASTIGFGDIV------PTKQLYVLIVFPYILLGLSLVSNCFRLNQ--------------EAAHWVDERF------------------CGARRV #=GC scorecons 0110101101111121322435412200000001032223334362116412632493334343110344525233253434200010002110132232433332232443533434323000003333524324344553734754799999345539439745464965597664633743475543543424334433239000432300000000003325243663234456555234453340000322745471544983849569799995700000074334533533443556667594453733000000000000003334322353223011112111311000101000 #=GC scorecons_70 ________________________________________________________*_____________________________________________________________________________________*__*__******_____*__**___*_*___**_*____*___*__________________*_________________________*______*__________________*___*____**_*_*_*******_*______*________________***_*____*__________________________________________________ #=GC scorecons_80 ________________________________________________________*_____________________________________________________________________________________*_____******_____*__*______*___**______*______________________*___________________________________________________*___*____**_*_*__******________*__________________*_*____*__________________________________________________ #=GC scorecons_90 ________________________________________________________*____________________________________________________________________________________________*****_____*__*______*___*______________________________*____________________________________________________________*____*__*_****_____________________________*_______________________________________________________ //