The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Arf Nucleotide-binding Site Opener,domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Cytohesin 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 13 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ARF guanyl-nucleotide exchange factor activity GO:0005086
Stimulates the exchange of guanyl nucleotides associated with the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
54 O08967 (/ISS) O08967 (/ISS) O08967 (/ISS) O08967 (/ISS) P63035 (/ISS) P97694 (/ISS) P97694 (/ISS) P97696 (/ISS) Q0E8N2 (/ISS) Q2KI41 (/ISS)
(44 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
36 O08967 (/IPI) O08967 (/IPI) O08967 (/IPI) O08967 (/IPI) O43739 (/IPI) O43739 (/IPI) O43739 (/IPI) P63034 (/IPI) P63034 (/IPI) P63035 (/IPI)
(26 more)
Inositol 1,4,5 trisphosphate binding GO:0070679
Interacting selectively and non-covalently with inositol 1,4,5 trisphosphate.
33 P63035 (/ISS) Q2KI41 (/ISS) Q76MY7 (/ISS) Q76MY7 (/ISS) Q76MY7 (/ISS) Q76MY7 (/ISS) Q76MY7 (/ISS) Q76MY7 (/ISS) Q76MY7 (/ISS) Q76MY7 (/ISS)
(23 more)
ARF guanyl-nucleotide exchange factor activity GO:0005086
Stimulates the exchange of guanyl nucleotides associated with the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
23 Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q99418 (/TAS)
(13 more)
ARF guanyl-nucleotide exchange factor activity GO:0005086
Stimulates the exchange of guanyl nucleotides associated with the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
17 O43739 (/IDA) O43739 (/IDA) O43739 (/IDA) P63034 (/IDA) P63034 (/IDA) Q15438 (/IDA) Q15438 (/IDA) Q15438 (/IDA) Q15438 (/IDA) Q15438 (/IDA)
(7 more)
Phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547
Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
11 O08967 (/IDA) O08967 (/IDA) O08967 (/IDA) O08967 (/IDA) O13690 (/IDA) O43739 (/IDA) O43739 (/IDA) O43739 (/IDA) Q0E8N2 (/IDA) Q9V9Q6 (/IDA)
(1 more)
ARF guanyl-nucleotide exchange factor activity GO:0005086
Stimulates the exchange of guanyl nucleotides associated with the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
9 O08967 (/ISO) O08967 (/ISO) O08967 (/ISO) O08967 (/ISO) Q10491 (/ISO) Q80YW0 (/ISO) Q80YW0 (/ISO) Q9QX11 (/ISO) Q9QX11 (/ISO)
Guanyl-nucleotide exchange factor activity GO:0005085
Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
4 O08967 (/ISS) O08967 (/ISS) O08967 (/ISS) O08967 (/ISS)
Phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547
Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
4 O08967 (/ISO) O08967 (/ISO) O08967 (/ISO) O08967 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
3 Q0E8N2 (/IPI) Q9V9Q6 (/IPI) Q9V9Q6 (/IPI)
Phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547
Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
2 P97696 (/ISS) Q5ZIG9 (/ISS)
Inositol 1,4,5 trisphosphate binding GO:0070679
Interacting selectively and non-covalently with inositol 1,4,5 trisphosphate.
2 P63034 (/IDA) P63034 (/IDA)
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
1 Q15795 (/NAS)

There are 40 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
14 Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS)
(4 more)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
14 Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS)
(4 more)
Establishment of epithelial cell polarity GO:0090162
The specification and formation of anisotropic intracellular organization of an epithelial cell.
14 O43739 (/ISS) O43739 (/ISS) O43739 (/ISS) P97694 (/ISS) P97694 (/ISS) Q15438 (/ISS) Q15438 (/ISS) Q15438 (/ISS) Q15438 (/ISS) Q15438 (/ISS)
(4 more)
Epiboly involved in gastrulation with mouth forming second GO:0055113
The expansion of one cell sheet over other cells involved in deuterostomic gastrulation.
11 A0A2R8QK04 (/IGI) A0A2R8QTS0 (/IGI) A2BHI2 (/IGI) E7F2Q0 (/IGI) F1QDR1 (/IGI) F1R9I9 (/IGI) F1RBL6 (/IGI) Q08CQ5 (/IGI) Q6PC26 (/IGI) Q6PW01 (/IGI)
(1 more)
Vesicle-mediated transport GO:0016192
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
9 Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS)
Regulation of cell adhesion GO:0030155
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
9 Q15438 (/IDA) Q15438 (/IDA) Q15438 (/IDA) Q15438 (/IDA) Q15438 (/IDA) Q15438 (/IDA) Q15438 (/IDA) Q15438 (/IDA) Q15438 (/IDA)
Establishment of epithelial cell polarity GO:0090162
The specification and formation of anisotropic intracellular organization of an epithelial cell.
6 O08967 (/IMP) O08967 (/IMP) O08967 (/IMP) O08967 (/IMP) Q9QX11 (/IMP) Q9QX11 (/IMP)
Golgi vesicle transport GO:0048193
The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
5 O08967 (/ISS) O08967 (/ISS) O08967 (/ISS) O08967 (/ISS) P97696 (/ISS)
Positive regulation of cell adhesion GO:0045785
Any process that activates or increases the frequency, rate or extent of cell adhesion.
4 O08967 (/IDA) O08967 (/IDA) O08967 (/IDA) O08967 (/IDA)
Golgi vesicle transport GO:0048193
The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
4 O08967 (/ISO) O08967 (/ISO) O08967 (/ISO) O08967 (/ISO)
Embryonic development via the syncytial blastoderm GO:0001700
The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.
3 Q0E8N2 (/IMP) Q9V9Q6 (/IMP) Q9V9Q6 (/IMP)
Regulation of endocytosis GO:0030100
Any process that modulates the frequency, rate or extent of endocytosis.
3 Q0E8N2 (/IMP) Q9V9Q6 (/IMP) Q9V9Q6 (/IMP)
Positive regulation of ARF protein signal transduction GO:0032014
Any process that activates or increases the frequency, rate or extent of ARF protein signal transduction.
3 Q0E8N2 (/ISS) Q9V9Q6 (/ISS) Q9V9Q6 (/ISS)
Regulation of actin cytoskeleton organization GO:0032956
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
3 Q0E8N2 (/IMP) Q9V9Q6 (/IMP) Q9V9Q6 (/IMP)
Golgi vesicle transport GO:0048193
The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
3 O43739 (/IMP) O43739 (/IMP) O43739 (/IMP)
Intracellular protein transport GO:0006886
The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
2 O13817 (/IC) Q10491 (/IC)
Exocytosis GO:0006887
A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.
2 O13817 (/ISO) Q10491 (/ISO)
Signaling GO:0023052
The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
2 O13817 (/NAS) Q10491 (/NAS)
Regulation of cell adhesion GO:0030155
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
2 P63034 (/ISO) P63034 (/ISO)
Negative regulation of dendrite development GO:2000171
Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development.
2 P63034 (/ISO) P63034 (/ISO)
Regulation of synaptic vesicle exocytosis GO:2000300
Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.
2 P97694 (/IDA) P97694 (/IDA)
Regulation of synaptic vesicle exocytosis GO:2000300
Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.
2 P97694 (/IMP) P97694 (/IMP)
Regulation of synaptic vesicle exocytosis GO:2000300
Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.
2 Q9QX11 (/ISO) Q9QX11 (/ISO)
Intracellular protein transport GO:0006886
The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
1 O13690 (/ISM)
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
1 Q15795 (/TAS)
Integrin-mediated signaling pathway GO:0007229
A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 Q15795 (/TAS)
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
1 Q0E8N2 (/IMP)
Imaginal disc-derived wing vein specification GO:0007474
The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified.
1 Q0E8N2 (/IMP)
Positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
1 Q0E8N2 (/IMP)
Vesicle-mediated transport GO:0016192
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
1 O13690 (/ISM)
Signaling GO:0023052
The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
1 O13690 (/IC)
Positive regulation of multicellular organism growth GO:0040018
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
1 Q0E8N2 (/IMP)
Positive regulation of epidermal growth factor receptor signaling pathway GO:0045742
Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
1 Q0E8N2 (/IMP)
Positive regulation of cell adhesion GO:0045785
Any process that activates or increases the frequency, rate or extent of cell adhesion.
1 Q5ZIG9 (/ISS)
Positive regulation of insulin receptor signaling pathway GO:0046628
Any process that increases the frequency, rate or extent of insulin receptor signaling.
1 Q0E8N2 (/IMP)
Cell growth mode switching, monopolar to bipolar GO:0051523
The process in which a cell switches from monopolar cell growth to bipolar cell growth.
1 O13690 (/IMP)
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
1 Q0E8N2 (/IMP)
Regulation of actomyosin structure organization GO:0110020
Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin.
1 Q0E8N2 (/IMP)
Negative regulation of dendrite development GO:2000171
Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development.
1 P63035 (/IMP)
Positive regulation of cAMP-dependent protein kinase activity GO:2000481
Any process that activates or increases the frequency, rate or extent of cAMP-dependent protein kinase activity.
1 Q0E8N2 (/IMP)

There are 43 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
36 O08967 (/IDA) O08967 (/IDA) O08967 (/IDA) O08967 (/IDA) O43739 (/IDA) O43739 (/IDA) O43739 (/IDA) Q0E8N2 (/IDA) Q15438 (/IDA) Q15438 (/IDA)
(26 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
29 P63034 (/ISS) P63034 (/ISS) P63035 (/ISS) P97694 (/ISS) P97694 (/ISS) P97696 (/ISS) Q2KI41 (/ISS) Q5ZIG9 (/ISS) Q76MY7 (/ISS) Q76MY7 (/ISS)
(19 more)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
27 O43739 (/TAS) O43739 (/TAS) O43739 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS)
(17 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
27 O08967 (/IDA) O08967 (/IDA) O08967 (/IDA) O08967 (/IDA) Q15438 (/IDA) Q15438 (/IDA) Q15438 (/IDA) Q15438 (/IDA) Q15438 (/IDA) Q15438 (/IDA)
(17 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
27 O43739 (/TAS) O43739 (/TAS) O43739 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS) Q15438 (/TAS)
(17 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
25 O08967 (/ISS) O08967 (/ISS) O08967 (/ISS) O08967 (/ISS) P97694 (/ISS) P97694 (/ISS) P97696 (/ISS) Q15438 (/ISS) Q15438 (/ISS) Q15438 (/ISS)
(15 more)
Extrinsic component of cytoplasmic side of plasma membrane GO:0031234
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.
25 O08967 (/ISS) O08967 (/ISS) O08967 (/ISS) O08967 (/ISS) P97694 (/ISS) P97694 (/ISS) P97696 (/ISS) Q15438 (/ISS) Q15438 (/ISS) Q15438 (/ISS)
(15 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
22 P63034 (/ISS) P63034 (/ISS) P63035 (/ISS) Q2KI41 (/ISS) Q5ZIG9 (/ISS) Q76MY7 (/ISS) Q76MY7 (/ISS) Q76MY7 (/ISS) Q76MY7 (/ISS) Q76MY7 (/ISS)
(12 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
14 Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS)
(4 more)
Bicellular tight junction GO:0005923
An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
14 O43739 (/ISS) O43739 (/ISS) O43739 (/ISS) P97694 (/ISS) P97694 (/ISS) Q15438 (/ISS) Q15438 (/ISS) Q15438 (/ISS) Q15438 (/ISS) Q15438 (/ISS)
(4 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
14 Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS) Q99418 (/TAS)
(4 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
10 O08967 (/ISO) O08967 (/ISO) O08967 (/ISO) O08967 (/ISO) P63034 (/ISO) P63034 (/ISO) Q80YW0 (/ISO) Q80YW0 (/ISO) Q9QX11 (/ISO) Q9QX11 (/ISO)
Bicellular tight junction GO:0005923
An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
8 O08967 (/IDA) O08967 (/IDA) O08967 (/IDA) O08967 (/IDA) P63034 (/IDA) P63034 (/IDA) Q9QX11 (/IDA) Q9QX11 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 O13817 (/HDA) Q0E8N2 (/HDA) Q10491 (/HDA) Q9V9Q6 (/HDA) Q9V9Q6 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 O43739 (/IDA) O43739 (/IDA) O43739 (/IDA) Q9QX11 (/IDA) Q9QX11 (/IDA)
Extrinsic component of cytoplasmic side of plasma membrane GO:0031234
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.
5 O43739 (/IDA) O43739 (/IDA) O43739 (/IDA) Q9QX11 (/IDA) Q9QX11 (/IDA)
Ruffle GO:0001726
Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.
4 O08967 (/IPI) O08967 (/IPI) O08967 (/IPI) O08967 (/IPI)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
4 O08967 (/ISO) O08967 (/ISO) O08967 (/ISO) O08967 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 O08967 (/ISO) O08967 (/ISO) O08967 (/ISO) O08967 (/ISO)
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
4 O08967 (/IDA) O08967 (/IDA) O08967 (/IDA) O08967 (/IDA)
Extrinsic component of cytoplasmic side of plasma membrane GO:0031234
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.
4 O08967 (/ISO) O08967 (/ISO) O08967 (/ISO) O08967 (/ISO)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
3 Q0E8N2 (/ISS) Q9V9Q6 (/ISS) Q9V9Q6 (/ISS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 O43739 (/IDA) O43739 (/IDA) O43739 (/IDA)
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
3 O43739 (/ISS) O43739 (/ISS) O43739 (/ISS)
Cleavage furrow GO:0032154
The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm.
3 Q0E8N2 (/IDA) Q9V9Q6 (/IDA) Q9V9Q6 (/IDA)
Ruffle GO:0001726
Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.
2 P63034 (/ISO) P63034 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P63034 (/ISO) P63034 (/ISO)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
2 O13690 (/IDA) Q0E8N2 (/IDA)
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
2 P97694 (/IDA) P97694 (/IDA)
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
2 P97694 (/IMP) P97694 (/IMP)
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
2 Q9QX11 (/ISO) Q9QX11 (/ISO)
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
2 O13817 (/HDA) Q10491 (/HDA)
Cell tip GO:0051286
The region at the end of the longest axis of a cylindrical or elongated cell.
2 O13817 (/HDA) Q10491 (/HDA)
Extrinsic component of presynaptic membrane GO:0098888
The component of the presynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
2 P97694 (/IDA) P97694 (/IDA)
Extrinsic component of presynaptic membrane GO:0098888
The component of the presynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
2 P97694 (/IMP) P97694 (/IMP)
Extrinsic component of presynaptic membrane GO:0098888
The component of the presynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
2 Q9QX11 (/ISO) Q9QX11 (/ISO)
Extrinsic component of postsynaptic specialization membrane GO:0098892
The component of the postsynaptic specialization membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
2 P63034 (/ISO) P63034 (/ISO)
Ruffle GO:0001726
Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.
1 P63035 (/IDA)
Ruffle GO:0001726
Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.
1 Q5ZIG9 (/ISS)
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
1 O13690 (/IDA)
Cell cortex of cell tip GO:0051285
The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell.
1 O13690 (/IDA)
Extrinsic component of postsynaptic specialization membrane GO:0098892
The component of the postsynaptic specialization membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
1 P63035 (/IDA)
Cell leading edge cell cortex GO:1904269
The cell cortex of the leading edge of a cell.
1 Q0E8N2 (/IDA)