CATH Classification

Domain Context

CATH Clusters

Superfamily Collagenase (Catalytic Domain)
Functional Family Astacin

Enzyme Information

3.4.24.21
Astacin.
based on mapping to UniProt P07584
Hydrolysis of peptide bonds in substrates containing five or more amino acids, preferentially with Ala in P1', and Pro in P2'.
-!- A digestive endopeptidase from the cardia of the crayfish Astacus fluviatilis. -!- Belongs to peptidase family M12A. -!- Formerly EC 3.4.99.6.

UniProtKB Entries (2)

Q9QXC1
FETUB_MOUSE
Mus musculus
Fetuin-B
P07584
ASTA_ASTAS
Astacus astacus
Astacin

PDB Structure

PDB 6HT9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition.
Cuppari, A., Korschgen, H., Fahrenkamp, D., Schmitz, C., Guevara, T., Karmilin, K., Kuske, M., Olf, M., Dietzel, E., Yiallouros, I., de Sanctis, D., Goulas, T., Weiskirchen, R., Jahnen-Dechent, W., Floehr, J., Stoecker, W., Jovine, L., Gomis-Ruth, F.X.
Iucrj