1 keywords

CATH Domain 6h1iA01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.120 Jelly Rolls
Homologous Superfamily 2.60.120.10 Jelly Rolls

Domain Context

CATH Clusters

Superfamily Jelly Rolls
Functional Family Pirin

Enzyme Information

1.13.11.24
Quercetin 2,3-dioxygenase.
based on mapping to UniProt O00625
Quercetin + O(2) = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO + H(+).
-!- Quercetin is a flavonol (5,7,3',4'-tetrahydroxyflavonol).

UniProtKB Entries (1)

O00625
PIR_HUMAN
Homo sapiens
Pirin

PDB Structure

PDB 6H1I
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Privileged Structures and Polypharmacology within and between Protein Families.
Meyers, J., Chessum, N.E.A., Ali, S., Mok, N.Y., Wilding, B., Pasqua, A.E., Rowlands, M., Tucker, M.J., Evans, L.E., Rye, C.S., O'Fee, L., Le Bihan, Y.V., Burke, R., Carter, M., Workman, P., Blagg, J., Brown, N., van Montfort, R.L.M., Jones, K., Cheeseman, M.D.
ACS Med Chem Lett