CATH Classification

Domain Context

CATH Clusters

Superfamily 3.90.940.10
Functional Family DNA-directed RNA polymerase subunit omega

Enzyme Information

2.7.7.6
DNA-directed RNA polymerase.
based on mapping to UniProt P0A800
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized. -!- See also EC 2.7.7.19 and EC 2.7.7.48.

UniProtKB Entries (1)

P0AFW0
RFAH_ECOLI
Escherichia coli K-12
Transcription antitermination protein RfaH

PDB Structure

PDB 6C6S
External Links
Method ELECTRON MICROSCOPY
Organism
Primary Citation
Structural Basis for Transcript Elongation Control by NusG Family Universal Regulators.
Kang, J.Y., Mooney, R.A., Nedialkov, Y., Saba, J., Mishanina, T.V., Artsimovitch, I., Landick, R., Darst, S.A.
Cell