CATH Classification

Domain Context

CATH Clusters

Superfamily DNA polymerase, thumb domain
Functional Family Repair DNA polymerase X

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P42494
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P42494
DPOLX_ASFB7
African swine fever virus BA71V
Repair DNA polymerase X

PDB Structure

PDB 5XMA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of an RNA-cleaving DNAzyme.
Liu, H., Yu, X., Chen, Y., Zhang, J., Wu, B., Zheng, L., Haruehanroengra, P., Wang, R., Li, S., Lin, J., Li, J., Sheng, J., Huang, Z., Ma, J., Gan, J.
Nat Commun