CATH Classification

Domain Context

CATH Clusters

Superfamily Dehydroquinate synthase-like - alpha domain
Functional Family 3-dehydroquinate synthase protein

Enzyme Information

4.2.3.154
Demethyl-4-deoxygadusol synthase.
based on mapping to UniProt Q3M6C3
D-sedoheptulose 7-phosphate = demethyl-4-deoxygadusol + phosphate + H(2)O.
-!- The enzyme, characterized from the cyanobacterium Nostoc punctiforme PCC 73102, is involved in the biosynthesis of the sunscreen compound shinorine. -!- Cf. EC 4.2.3.152 and EC 4.2.3.155.

UniProtKB Entries (1)

Q3M6C3
DDGS_ANAVT
Trichormus variabilis ATCC 29413
Demethyl-4-deoxygadusol synthase

PDB Structure

PDB 5TPR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Evolution and Distribution of C7-Cyclitol Synthases in Prokaryotes and Eukaryotes.
Osborn, A.R., Kean, K.M., Alseud, K.M., Almabruk, K.H., Asamizu, S., Lee, J.A., Karplus, P.A., Mahmud, T.
ACS Chem. Biol.