CATH Classification

Domain Context

CATH Clusters

Superfamily 2.10.110.40
Functional Family E1A binding protein p300

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt Q09472
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
2.3.1.-
Transferring groups other than amino-acyl groups.
based on mapping to UniProt Q09472

UniProtKB Entries (1)

Q09472
EP300_HUMAN
Homo sapiens
Histone acetyltransferase p300

PDB Structure

PDB 5LKZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of p300 in complex with acyl-CoA variants.
Kaczmarska, Z., Ortega, E., Goudarzi, A., Huang, H., Kim, S., Marquez, J.A., Zhao, Y., Khochbin, S., Panne, D.
Nat. Chem. Biol.