CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family RNA helicase, activating signal cointegrator 1

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt P32639
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

Q12330
RUXE_YEAST
Saccharomyces cerevisiae S288C
Small nuclear ribonucleoprotein E

PDB Structure

PDB 5LJ5
External Links
Method ELECTRON MICROSCOPY
Organism
Primary Citation
Cryo-EM structure of the spliceosome immediately after branching.
Galej, W.P., Wilkinson, M.E., Fica, S.M., Oubridge, C., Newman, A.J., Nagai, K.
Nature