CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.130 | 7 Propeller |
|
2.130.10 | Methylamine Dehydrogenase; Chain H |
|
2.130.10.10 | YVTN repeat-like/Quinoprotein amine dehydrogenase |
Domain Context
CATH Clusters
| Superfamily | YVTN repeat-like/Quinoprotein amine dehydrogenase |
| Functional Family | DDB1 and CUL4-associated factor 1 |
Enzyme Information
| 2.7.11.1 |
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q9Y4B6
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
|
UniProtKB Entries (2)
| P12520 |
VPR_HV1N5
Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)
Protein Vpr
|
| Q9Y4B6 |
DCAF1_HUMAN
Homo sapiens
DDB1- and CUL4-associated factor 1
|
PDB Structure
| PDB | 5JK7 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction.
Nat.Struct.Mol.Biol.
|