CATH Classification

Domain Context

CATH Clusters

Superfamily Tetracycline Repressor, domain 2
Functional Family HTH-type transcriptional regulator EthR

Enzyme Information

UniProtKB Entries (1)

A5U9I4
A5U9I4_MYCTA
Mycobacterium tuberculosis H37Ra
TetR-family transcriptional regulatory repressor protein

PDB Structure

PDB 5IP6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays.
Nikiforov, P.O., Blaszczyk, M., Surade, S., Boshoff, H.I., Sajid, A., Delorme, V., Deboosere, N., Brodin, P., Baulard, A.R., Barry, C.E., Blundell, T.L., Abell, C.
ACS Chem. Biol.