CATH Classification

Domain Context

CATH Clusters

Superfamily Serralysin-like metalloprotease, C-terminal
Functional Family Serralysin

Enzyme Information

3.4.24.40
Serralysin.
based on mapping to UniProt P23694
Preferential cleavage of bonds with hydrophobic residues in P1'.
-!- An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi. -!- There is broad specificity in cleavage of the insulin B chain, with some species variations. -!- The pH optimum for digesting various proteins is about 9-10. -!- Belongs to peptidase family M10A. -!- Formerly EC 3.4.24.4.

UniProtKB Entries (1)

P23694
PRZN_SERMA
Serratia marcescens
Serralysin

PDB Structure

PDB 5D7W
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of a thermostable serralysin from Serratia sp. FS14 at 1.1 angstrom resolution.
Wu, D., Ran, T., Wang, W., Xu, D.
Acta Crystallogr.,Sect.F