CATH Classification

Domain Context

CATH Clusters

Superfamily Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Functional Family Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase

Enzyme Information

3.5.1.118
Gamma-glutamyl hercynylcysteine S-oxide hydrolase.
based on mapping to UniProt A0R5M9
Gamma-L-glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide + H(2)O = S-(hercyn- 2-yl)-L-cysteine S-oxide + L-glutamate.
-!- The enzyme is part of the biosynthesis pathway of ergothioneine in mycobacteria.

UniProtKB Entries (1)

A0R5M9
EGTC_MYCS2
Mycolicibacterium smegmatis MC2 155
Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase

PDB Structure

PDB 4ZFL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtC.
Vit, A., Mashabela, G.T., Blankenfeldt, W., Seebeck, F.P.
Chembiochem