CATH Classification

Domain Context

CATH Clusters

Superfamily 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1
Functional Family Lactoylglutathione lyase

Enzyme Information

4.4.1.5
Lactoylglutathione lyase.
based on mapping to UniProt Q9CPU0
(R)-S-lactoylglutathione = glutathione + methylglyoxal.
-!- Also acts on 3-phosphoglycerol-glutathione.

UniProtKB Entries (1)

Q9CPU0
LGUL_MOUSE
Mus musculus
Lactoylglutathione lyase

PDB Structure

PDB 4X2A
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
In Vitro Inhibition of Glyoxalase І by Flavonoids: New Insights from Crystallographic Analysis.
Zhang, H., Zhai, J., Zhang, L., Li, C., Zhao, Y., Chen, Y., Li, Q., Hu, X.P.
Curr Top Med Chem