CATH Classification

Domain Context

CATH Clusters

Superfamily Divalent-metal-dependent TIM barrel enzymes
Functional Family

Enzyme Information

5.1.3.31
D-tagatose 3-epimerase.
based on mapping to UniProt O50580
(1) D-tagatose = D-sorbose. (2) D-psicose = D-fructose.
-!- The enzymes isolated from the bacteria Pseudomonas cichorii, Pseudomonas sp. ST-24, Rhodobacter sphaeroides and Mesorhizobium loti catalyze the epimerization of various ketoses at the C(3) position, interconverting D-fructose and D-psicose, D-tagatose and D-sorbose, D-ribulose and D-xylulose, and L-ribulose and L-xylulose. -!- The specificity depends on the species.

UniProtKB Entries (1)

O50580
DT3E_PSECI
Pseudomonas cichorii
D-tagatose 3-epimerase

PDB Structure

PDB 4PGL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Directed Divergent Evolution of a Thermostable D-Tagatose Epimerase towards Improved Activity for Two Hexose Substrates.
Bosshart, A., Hee, C.S., Bechtold, M., Schirmer, T., Panke, S.
Chembiochem