CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Casein kinase II subunit alpha

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P15790
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P15790
CSK21_YEAST
Saccharomyces cerevisiae S288C
Casein kinase II subunit alpha

PDB Structure

PDB 4MWH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway.
Liu, H., Wang, H., Teng, M., Li, X.
Acta Crystallogr.,Sect.D