CATH Classification

Domain Context

CATH Clusters

Superfamily Putative phosphatase; domain 2
Functional Family HAD hydrolase, family IA, variant 3

Enzyme Information

3.1.3.-
Phosphoric monoester hydrolases.
based on mapping to UniProt Q8A947
3.1.3.104
5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase.
based on mapping to UniProt Q8A947
5-amino-6-(5-phospho-D-ribitylamino)uracil + H(2)O = 5-amino-6- (D-ribitylamino)uracil + phosphate.
-!- The enzyme, which is found in plants and bacteria, is part of a pathway for riboflavin biosynthesis. -!- Most forms of the enzyme has a broad substrate specificity.

UniProtKB Entries (1)

Q8A947
RIBX_BACTN
Bacteroides thetaiotaomicron VPI-5482
D-ribitol-5-phosphate phosphatase

PDB Structure

PDB 4JB3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of bt_0970, a had family phosphatase from bacteroides thetaiotaomicron VPI-5482, TARGET EFI-501083, with bound sodium and glycerol, closed lid, ordered loop
Vetting, M.W., Toro, R., Bhosle, R., Kumar, P.R., Ghosh, A., Al Obaidi, N.F., Stead, M., Washington, E., Scott Glenn, A., Chowdhury, S., Evans, B., Hammonds, J., Hillerich, B., Love, J., Seidel, R.D., Imker, H.J., Dunaway-Mariano, D., Allen, K.N., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
To be Published