CATH Domain 4i51A00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.170	Beta Complex
	2.170.270	Beta-clip-like
	2.170.270.10	SET domain

Domain Context

CATH Clusters

Superfamily	SET domain
Functional Family	Euchromatic histone-lysine N-methyltransferase 2

Enzyme Information

2.1.1.-	Methyltransferases. based on mapping to UniProt Q9H9B1
2.1.1.43	Histone-lysine N-methyltransferase. based on mapping to UniProt Q9H9B1 S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

H31_HUMAN

Homo sapiens

Histone H3.1

PDB Structure

PDB	4I51
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation. Islam, K., Chen, Y., Wu, H., Bothwell, I.R., Blum, G.J., Zeng, H., Dong, A., Zheng, W., Min, J., Deng, H., Luo, M. Proc.Natl.Acad.Sci.USA