CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family

Enzyme Information

2.7.6.1
Ribose-phosphate diphosphokinase.
based on mapping to UniProt P60891
ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- dATP can also act as donor.

UniProtKB Entries (1)

P60891
PRPS1_HUMAN
Homo sapiens
Ribose-phosphate pyrophosphokinase 1

PDB Structure

PDB 4F8E
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A small disturbance, but a serious disease: the possible mechanism of D52H-mutant of human PRS1 that causes gout
Chen, P., Li, J., Ma, J., Teng, M., Li, X.
Iubmb Life