CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Probable GDP-L-fucose synthase |
Enzyme Information
| 1.1.1.271 |
GDP-L-fucose synthase.
based on mapping to UniProt Q13630
GDP-beta-L-fucose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + NADPH.
-!- Both human and Escherichia coli enzymes can use NADH in place of NADPH to a slight extent.
|
UniProtKB Entries (1)
| Q13630 |
FCL_HUMAN
Homo sapiens
GDP-L-fucose synthase
|
PDB Structure
| PDB | 4E5Y |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of human FX protein, the key enzyme in the biosynthesis of GDP-L-fucose
To be Published
|