CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.1090 | Fimbrial-type adhesion domain |
Domain Context
CATH Clusters
| Superfamily | Fimbrial-type adhesion domain |
| Functional Family | Type 1 fimbrin D-mannose specific adhesin |
Enzyme Information
UniProtKB Entries (1)
| A2IC68 |
A2IC68_ECOLX
Escherichia coli
FimH
|
PDB Structure
| PDB | 4CA4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Mutation of Tyr137 of the universal Escherichia coli fimbrial adhesin FimH relaxes the tyrosine gate prior to mannose binding.
IUCrJ
|