CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family

Enzyme Information

2.7.10.2
Non-specific protein-tyrosine kinase.
based on mapping to UniProt P51813
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P51813
BMX_HUMAN
Homo sapiens
Cytoplasmic tyrosine-protein kinase BMX

PDB Structure

PDB 3SXS
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
X-ray crystal structure of bone marrow kinase in the x chromosome: a Tec family kinase.
Muckelbauer, J., Sack, J.S., Ahmed, N., Burke, J., Chang, C.Y., Gao, M., Tino, J., Xie, D., Tebben, A.J.
Chem.Biol.Drug Des.