CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family receptor-type tyrosine-protein phosphatase delta isoform X2

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt A2A8L5
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

A2A8L5
PTPRF_MOUSE
Mus musculus
Receptor-type tyrosine-protein phosphatase F

PDB Structure

PDB 3PXH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Immunoglobulin-like Domains 1 and 2 of the Protein Tyrosine Phosphatase LAR Adopt an Unusual Horseshoe-like Conformation.
Biersmith, B.H., Hammel, M., Geisbrecht, E.R., Bouyain, S.
J.Mol.Biol.