CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family tRNA dimethylallyltransferase

Enzyme Information

2.5.1.75
tRNA dimethylallyltransferase.
based on mapping to UniProt P16384
Dimethylallyl diphosphate + adenine(37) in tRNA = diphosphate + N(6)- dimethylallyladenine(37) in tRNA.
-!- Formerly known as tRNA isopentenyltransferase (EC 2.5.1.8), but it is now known that dimethylallyl diphosphate, rather than isopentenyl diphosphate, is the substrate. -!- Formerly EC 1.8.6.1 and EC 2.5.1.8.

UniProtKB Entries (1)

P16384
MIAA_ECOLI
Escherichia coli K-12
TRNA dimethylallyltransferase

PDB Structure

PDB 3FOZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
RNA-Protein Mutually Induced Fit: STRUCTURE OF ESCHERICHIA COLI ISOPENTENYL-tRNA TRANSFERASE IN COMPLEX WITH tRNA(Phe).
Seif, E., Hallberg, B.M.
J.Biol.Chem.