CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Thymidine kinase

Enzyme Information

2.7.1.21
Thymidine kinase.
based on mapping to UniProt Q0H0G9
ATP + thymidine = ADP + thymidine 5'-phosphate.
-!- Deoxyuridine can also act as acceptor. -!- dGTP can also act as donor. -!- The deoxypyrimidine kinase complex induced by Herpes simplex virus catalyzes this reaction as well as those of EC 2.7.1.114, EC 2.7.1.118 and EC 2.7.4.9. -!- Formerly EC 2.7.1.75.

UniProtKB Entries (1)

Q0H0G9
Q0H0G9_STAAU
Staphylococcus aureus
Thymidine kinase

PDB Structure

PDB 3E2I
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of Thymidine Kinase from S. aureus
Lam, R., Johns, K., Battaile, K.P., Romanov, V., Lam, K., Pai, E.F., Chirgadze, N.Y.
To be Published