CATH Classification

Domain Context

CATH Clusters

Superfamily Adenosylhomocysteinase-like
Functional Family

Enzyme Information

3.3.1.1
Adenosylhomocysteinase.
based on mapping to UniProt Q3JY79
S-adenosyl-L-homocysteine + H(2)O = L-homocysteine + adenosine.
-!- The NAD(+) cofactor appears to bring about a transient oxidation at C-3' of the 5'-deoxyadenosine residue, thus labilizing the thioether bond cf. EC 5.5.1.4.

UniProtKB Entries (1)

Q3JY79
SAHH_BURP1
Burkholderia pseudomallei 1710b
Adenosylhomocysteinase

PDB Structure

PDB 3D64
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of S-adenosyl-L-homocysteine hydrolase from Burkholderia pseudomallei.
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
To be Published