CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.3380.30
Functional Family superkiller viralicidic activity 2-like 2

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt P47047
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

P47047
MTR4_YEAST
Saccharomyces cerevisiae S288C
ATP-dependent RNA helicase DOB1

PDB Structure

PDB 2XGJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Analysis Reveals the Characteristic Features of Mtr4, a Dexh Helicase Involved in Nuclear RNA Processing and Surveillance.
Weir, J.R., Bonneau, F., Hentschel, J., Conti, E.
Proc.Natl.Acad.Sci.USA