CATH Classification

Domain Context

CATH Clusters

Superfamily Endonuclease/exonuclease/phosphatase
Functional Family Sphingomyelinase C

Enzyme Information

3.1.4.12
Sphingomyelin phosphodiesterase.
based on mapping to UniProt P11889
Sphingomyelin + H(2)O = N-acylsphingosine + phosphocholine.
-!- Has very little activity on phosphatidylcholine.

UniProtKB Entries (1)

P11889
PHL2_BACCE
Bacillus cereus
Sphingomyelinase C

PDB Structure

PDB 2UYR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Bacillus Cereus Sphingomyelinase Mutant : N57A
Oda, M., Tsuge, H., Sakurai, J.
To be Published