CATH Classification

Domain Context

CATH Clusters

Superfamily Mur-like, catalytic domain
Functional Family UDP-N-acetylmuramoylalanine--D-glutamate ligase

Enzyme Information

6.3.2.9
UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase.
based on mapping to UniProt P14900
ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanine + D-glutamate = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate.
-!- Involved in the synthesis of a cell-wall peptide in bacteria.

UniProtKB Entries (1)

P14900
MURD_ECOLI
Escherichia coli K-12
UDP-N-acetylmuramoylalanine--D-glutamate ligase

PDB Structure

PDB 2UAG
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Determination of the MurD mechanism through crystallographic analysis of enzyme complexes.
Bertrand, J.A., Auger, G., Martin, L., Fanchon, E., Blanot, D., Le Beller, D., van Heijenoort, J., Dideberg, O.
J.Mol.Biol.