CATH Classification

Domain Context

CATH Clusters

Superfamily 1.50.10.10
Functional Family Mannosyl-oligosaccharide alpha-1,2-mannosidase

Enzyme Information

3.2.1.113
Mannosyl-oligosaccharide 1,2-alpha-mannosidase.
based on mapping to UniProt P31723
Hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2).
-!- Involved in the synthesis of glycoproteins.

UniProtKB Entries (1)

P31723
MAN12_PENCI
Penicillium citrinum
Mannosyl-oligosaccharide alpha-1,2-mannosidase

PDB Structure

PDB 2RI9
External Links
Method X-RAY DIFFRACTION
Organism Aspergillus
Primary Citation
Modulation of activity by Arg407: structure of a fungal alpha-1,2-mannosidase in complex with a substrate analogue.
Lobsanov, Y.D., Yoshida, T., Desmet, T., Nerinckx, W., Yip, P., Claeyssens, M., Herscovics, A., Howell, P.L.
Acta Crystallogr.,Sect.D