CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.180 | 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 |
|
3.10.180.10 | 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 |
Domain Context
CATH Clusters
| Superfamily | 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 |
| Functional Family | 4-hydroxymandelate synthase |
Enzyme Information
| 1.13.11.46 |
4-hydroxymandelate synthase.
based on mapping to UniProt O52791
4-hydroxyphenylpyruvate + O(2) = (S)-4-hydroxymandelate + CO(2).
-!- Involved in the biosynthesis of the vancomycin group of glycopeptide antibiotics.
|
UniProtKB Entries (1)
| O52791 |
HMAS_AMYOR
Amycolatopsis orientalis
4-hydroxymandelate synthase
|
PDB Structure
| PDB | 2R5V |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Two roads diverged: the structure of hydroxymandelate synthase from Amycolatopsis orientalis in complex with 4-hydroxymandelate.
Biochemistry
|