CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1170.60
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q9UBT6
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q9UBT6
POLK_HUMAN
Homo sapiens
DNA polymerase kappa

PDB Structure

PDB 2OH2
External Links
Method X-RAY DIFFRACTION
Organism Saccharomyces
Primary Citation
Ternary complex of the catalytic core of human DNA polymerase Kappa with DNA and dTT
Lone, S., Townson, S.A., Uljon, S.N., Johnson, R.E., Brahma, A., Nair, D.T., Prakash, S., Prakash, L., Aggarwal, A.K.
To be Published