CATH Classification

Domain Context

CATH Clusters

Superfamily 2.60.200.20
Functional Family Protein serine-threonine kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P39009
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P39009
DUN1_YEAST
Saccharomyces cerevisiae S288C
DNA damage response protein kinase DUN1

PDB Structure

PDB 2JQL
External Links
Method SOLUTION NMR
Organism
Primary Citation
Diphosphothreonine-specific interaction between an SQ/TQ cluster and an FHA domain in the Rad53-Dun1 kinase cascade.
Lee, H., Yuan, C., Hammet, A., Mahajan, A., Chen, E.S., Wu, M.R., Su, M.I., Heierhorst, J., Tsai, M.D.
Mol.Cell