CATH Classification

Domain Context

CATH Clusters

Superfamily Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family Probable 4-aminobutyrate aminotransferase

Enzyme Information

2.6.1.36
L-lysine 6-transaminase.
based on mapping to UniProt P9WQ77
L-lysine + 2-oxoglutarate = (S)-2-amino-6-oxohexanoate + L-glutamate.
-!- The product, (S)-2-amino-6-oxohexanoate, is converted into the intramolecularly dehydrated form, 1-piperideine 6-carboxylate.

UniProtKB Entries (1)

P9WQ77
LAT_MYCTU
Mycobacterium tuberculosis H37Rv
Probable L-lysine-epsilon aminotransferase

PDB Structure

PDB 2JJH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mutational Analysis of Mycobacterium Tuberculosis Lysine Epsilon-Aminotransferase and Inhibitor Co-Crystal Structures, Reveals Distinct Binding Modes.
Tripathi, S.M., Agarwal, A., Ramachandran, R.
Biochem.Biophys.Res.Commun.