CATH Classification

Domain Context

CATH Clusters

Superfamily SH2 domain
Functional Family Suppressor of cytokine signaling 5

Enzyme Information

UniProtKB Entries (1)

Q8WXH5
SOCS4_HUMAN
Homo sapiens
Suppressor of cytokine signaling 4

PDB Structure

PDB 2IZV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation.
Bullock, A.N., Rodriguez, M.C., Debreczeni, J.E., Songyang, Z., Knapp, S.
Structure