CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Carboxypeptidase

Enzyme Information

3.4.16.5
Carboxypeptidase C.
based on mapping to UniProt P00729
Release of a C-terminal amino acid with broad specificity.
-!- Carboxypeptidases of broad specificity with optimum pH 4.5-6.0, inhibited by the action of diisopropyl fluorophosphate, and sensitive to thiol-blocking reagents. -!- This enzyme is probably also identical to lysosomal tyrosine carboxypeptidase. -!- Belongs to peptidase family S10. -!- Formerly EC 3.4.12.1, EC 3.4.12.12, EC 3.4.16.1, EC 3.4.16.3 and EC 3.4.21.13.

UniProtKB Entries (1)

P00729
CBPY_YEAST
Saccharomyces cerevisiae S288C
Carboxypeptidase Y

PDB Structure

PDB 1YSC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
2.8-A structure of yeast serine carboxypeptidase
Endrizzi, J.A., Breddam, K., Remington, S.J.
Biochemistry