CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Ribosomal protein S6 kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O75582
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O75582
KS6A5_HUMAN
Homo sapiens
Ribosomal protein S6 kinase alpha-5

PDB Structure

PDB 1VZO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Structure of Msk1 Reveals a Novel Autoinhibitory Conformation for a Dual Kinase Protein
Smith, K.J., Carter, P.S., Bridges, A., Horrocks, P., Lewis, C., Pettman, G., Clarke, A., Brown, M., Hughes, J., Wilkinson, M., Bax, B., Reith, A.
Structure