CATH Classification
Domain Context
CATH Clusters
| Superfamily | Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A |
| Functional Family | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase |
Enzyme Information
| 2.7.7.60 |
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase.
based on mapping to UniProt Q9X1B3
CTP + 2-C-methyl-D-erythritol 4-phosphate = diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol.
-!- ATP or UTP can replace CTP, but both are less effective. -!- GTP and TTP are not substrates. -!- Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.
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UniProtKB Entries (1)
| Q9X1B3 |
ISPD_THEMA
Thermotoga maritima MSB8
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
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PDB Structure
| PDB | 1VPA |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (TM1393) from Thermotoga maritima at 2.67 A resolution
To be published
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