CATH Classification

Domain Context

CATH Clusters

Superfamily Alpha-L RNA-binding motif
Functional Family Pseudouridine synthase

Enzyme Information

5.4.99.19
16S rRNA pseudouridine(516) synthase.
based on mapping to UniProt P45124
16S rRNA uridine(516) = 16S rRNA pseudouridine(516).
-!- The enzyme is specific for uridine(516) in 16S rRNA. -!- In vitro, the enzyme does not modify free 16S rRNA. -!- The preferred substrate is a 5'-terminal fragment of 16S rRNA complexed with 30S ribosomal proteins.

UniProtKB Entries (1)

P45124
RSUA_HAEIN
Haemophilus influenzae Rd KW20
Ribosomal small subunit pseudouridine synthase A

PDB Structure

PDB 1VIO
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of the pseudouridine synthase RsuA from Haemophilus influenzae.
Matte, A., Louie, G.V., Sivaraman, J., Cygler, M., Burley, S.K.
Acta Crystallogr.,Sect.F