CATH Classification

Domain Context

CATH Clusters

Superfamily GHMP kinase, C-terminal domain
Functional Family

Enzyme Information

2.7.1.148
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase.
based on mapping to UniProt P83700
ATP + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = ADP + 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol.
-!- Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.

UniProtKB Entries (1)

P83700
ISPE_THET8
Thermus thermophilus HB8
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

PDB Structure

PDB 1UEK
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase, an Enzyme in the Non-mevalonate Pathway of Isoprenoid Synthesis.
Wada, T., Kuzuyama, T., Satoh, S., Kuramitsu, S., Yokoyama, S., Unzai, S., Tame, J.R., Park, S.Y.
J.Biol.Chem.